Determination of critical-sized defect of mandible in a rabbit model: Micro-computed tomography, and histological evaluation

Determination of critical-sized defect of mandible in a rabbit model: Micro-computed tomography, and histological evaluation

Objective: To evaluate a rabbit model of mandibular box-shaped defects created through an intraoral approach and determine the minimum size defect that would not spontaneously heal during the rabbit's natural life (or critical-sized defect, CSD). Methods: Forty-five 6-month-old rabbits were ran...

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Bibliographic Details
Main Authors: Yue Wang, Xiaoyan Zhang, Shuang Mei, Yunlong Li, Anas Ameer Khan, Shuai Guan, Xiangjun Li
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Rabbit
Laboratory animal
Mandibular defect
Bone loss
Critical-sized defect
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023052556

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