Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case Report
Vertebral body location of hemangioblastomas (HB) is extremely rare. The authors report a case of spinal mass involving lower thoracic region with cord compression, approved to be spinal HB. A 57-year-old man presented to our center with eight months history of progressive intractable back pain and...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-12-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/9952 |
| _version_ | 1827385704653520896 |
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| author | Hooshang Saberi Arad Iranmehr Nazi Derakhshanrad Abolfazl Payinmahalli Vahid Soleimani |
| author_facet | Hooshang Saberi Arad Iranmehr Nazi Derakhshanrad Abolfazl Payinmahalli Vahid Soleimani |
| author_sort | Hooshang Saberi |
| collection | DOAJ |
| description |
Vertebral body location of hemangioblastomas (HB) is extremely rare. The authors report a case of spinal mass involving lower thoracic region with cord compression, approved to be spinal HB. A 57-year-old man presented to our center with eight months history of progressive intractable back pain and paraparesis. Admission computed tomography and magnetic resonance imaging (MRI) of the thoracolumbar spine demonstrated a lytic and expansile spinal mass with pedicle expansion and vivid contrast enhancement involving T11 and T12 vertebral bodies on the right side. He was a known case of von Hippel-Lindau (VHL) and he had history of 4th ventricular asymptomatic hemangioblastoma near Obex, multiple pancreatic cystic adenomas, multiple liver cysts, and right non-chromaffin adrenal mass. The patient underwent a T11-T12 partial transpedicular corpectomy with T5 to L3 posterior spinal fixation to bridge the invaded segment. The pathological and immunohistochemical findings were consistent with vertebral HB. Spinal HB although extremely rare, may be managed with subtotal tumor resection and fixation of normal adjacent vertebrae by cemented screws.
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| first_indexed | 2024-03-08T15:30:18Z |
| format | Article |
| id | doaj.art-40d3f7bdafc94b35a68f2f90f5680ef5 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-03-08T15:30:18Z |
| publishDate | 2023-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-40d3f7bdafc94b35a68f2f90f5680ef52024-01-10T05:52:28ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942023-12-0161710.18502/acta.v61i7.14500Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case ReportHooshang Saberi0Arad Iranmehr1Nazi Derakhshanrad2Abolfazl Payinmahalli3Vahid Soleimani4Department of Neurosurgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranDepartment of Neurosurgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran0000-0002-4613-347XDepartment of Neurosurgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Vertebral body location of hemangioblastomas (HB) is extremely rare. The authors report a case of spinal mass involving lower thoracic region with cord compression, approved to be spinal HB. A 57-year-old man presented to our center with eight months history of progressive intractable back pain and paraparesis. Admission computed tomography and magnetic resonance imaging (MRI) of the thoracolumbar spine demonstrated a lytic and expansile spinal mass with pedicle expansion and vivid contrast enhancement involving T11 and T12 vertebral bodies on the right side. He was a known case of von Hippel-Lindau (VHL) and he had history of 4th ventricular asymptomatic hemangioblastoma near Obex, multiple pancreatic cystic adenomas, multiple liver cysts, and right non-chromaffin adrenal mass. The patient underwent a T11-T12 partial transpedicular corpectomy with T5 to L3 posterior spinal fixation to bridge the invaded segment. The pathological and immunohistochemical findings were consistent with vertebral HB. Spinal HB although extremely rare, may be managed with subtotal tumor resection and fixation of normal adjacent vertebrae by cemented screws. https://acta.tums.ac.ir/index.php/acta/article/view/9952VertebraeHemangioblastomaVon hippel-lindau diseaseClear cell carcinoma |
| spellingShingle | Hooshang Saberi Arad Iranmehr Nazi Derakhshanrad Abolfazl Payinmahalli Vahid Soleimani Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case Report Acta Medica Iranica Vertebrae Hemangioblastoma Von hippel-lindau disease Clear cell carcinoma |
| title | Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case Report |
| title_full | Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case Report |
| title_fullStr | Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case Report |
| title_full_unstemmed | Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case Report |
| title_short | Management of Spinal Hemangioblastoma in Von Hippel-Lindau Disease: A Case Report |
| title_sort | management of spinal hemangioblastoma in von hippel lindau disease a case report |
| topic | Vertebrae Hemangioblastoma Von hippel-lindau disease Clear cell carcinoma |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/9952 |
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