Association between body mass index and respiratory symptoms in US adults: a national cross-sectional study
Abstract The correlation between body mass index (BMI) and the development of cough, shortness of breath, and dyspnea is unclear. Therefore, this study aimed to investigate the association between these parameters. Data from individuals who participated in the National Health and Nutrition Examinati...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-51637-z |
| _version_ | 1797355777837498368 |
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| author | Yuefeng Sun Yueyang Zhang Xiangyang Liu Yingying Liu Fan Wu Xue Liu |
| author_facet | Yuefeng Sun Yueyang Zhang Xiangyang Liu Yingying Liu Fan Wu Xue Liu |
| author_sort | Yuefeng Sun |
| collection | DOAJ |
| description | Abstract The correlation between body mass index (BMI) and the development of cough, shortness of breath, and dyspnea is unclear. Therefore, this study aimed to investigate the association between these parameters. Data from individuals who participated in the National Health and Nutrition Examination Survey between 2003 and 2012 were analyzed. Weighted logistic regression analysis and smoothed curve fitting were used to examine the correlation between BMI and respiratory symptoms. In addition, the relationship between BMI, chronic obstructive pulmonary disease (COPD), and bronchial asthma was examined. Stratified analysis was used to discover inflection points and specific groups. Weighted logistic regression and smoothed curve fitting revealed a U-shaped relationship between BMI and respiratory symptoms. The U-shaped relationship in BMI was also observed in patients with bronchial asthma and COPD. Stratified analysis showed that the correlation between BMI and wheezing and dyspnea was influenced by race. In addition, non-Hispanic black individuals had a higher risk of developing cough than individuals of the other three races [OR 1.040 (1.021, 1.060), p < 0.0001], and they also exhibited an inverted U-shaped relationship between BMI and bronchial asthma. However, the association of BMI with cough, wheezing, dyspnea, COPD, and asthma was not affected by sex. High or low BMI was associated with cough, shortness of breath, and dyspnea, and has been linked to bronchial asthma and COPD. These findings provide new insights into the management of respiratory symptoms and respiratory diseases. |
| first_indexed | 2024-03-08T14:15:58Z |
| format | Article |
| id | doaj.art-40d4887ff3f64863a16d89efbe57be61 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-08T14:15:58Z |
| publishDate | 2024-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-40d4887ff3f64863a16d89efbe57be612024-01-14T12:21:54ZengNature PortfolioScientific Reports2045-23222024-01-0114111110.1038/s41598-024-51637-zAssociation between body mass index and respiratory symptoms in US adults: a national cross-sectional studyYuefeng Sun0Yueyang Zhang1Xiangyang Liu2Yingying Liu3Fan Wu4Xue Liu5The First Clinical Medical College, Shandong University of Traditional Chinese MedicineThe First Clinical Medical College, Shandong University of Traditional Chinese MedicineSchool of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineDepartment of Pulmonary and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese MedicineSchool of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineDepartment of Pulmonary and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese MedicineAbstract The correlation between body mass index (BMI) and the development of cough, shortness of breath, and dyspnea is unclear. Therefore, this study aimed to investigate the association between these parameters. Data from individuals who participated in the National Health and Nutrition Examination Survey between 2003 and 2012 were analyzed. Weighted logistic regression analysis and smoothed curve fitting were used to examine the correlation between BMI and respiratory symptoms. In addition, the relationship between BMI, chronic obstructive pulmonary disease (COPD), and bronchial asthma was examined. Stratified analysis was used to discover inflection points and specific groups. Weighted logistic regression and smoothed curve fitting revealed a U-shaped relationship between BMI and respiratory symptoms. The U-shaped relationship in BMI was also observed in patients with bronchial asthma and COPD. Stratified analysis showed that the correlation between BMI and wheezing and dyspnea was influenced by race. In addition, non-Hispanic black individuals had a higher risk of developing cough than individuals of the other three races [OR 1.040 (1.021, 1.060), p < 0.0001], and they also exhibited an inverted U-shaped relationship between BMI and bronchial asthma. However, the association of BMI with cough, wheezing, dyspnea, COPD, and asthma was not affected by sex. High or low BMI was associated with cough, shortness of breath, and dyspnea, and has been linked to bronchial asthma and COPD. These findings provide new insights into the management of respiratory symptoms and respiratory diseases.https://doi.org/10.1038/s41598-024-51637-z |
| spellingShingle | Yuefeng Sun Yueyang Zhang Xiangyang Liu Yingying Liu Fan Wu Xue Liu Association between body mass index and respiratory symptoms in US adults: a national cross-sectional study Scientific Reports |
| title | Association between body mass index and respiratory symptoms in US adults: a national cross-sectional study |
| title_full | Association between body mass index and respiratory symptoms in US adults: a national cross-sectional study |
| title_fullStr | Association between body mass index and respiratory symptoms in US adults: a national cross-sectional study |
| title_full_unstemmed | Association between body mass index and respiratory symptoms in US adults: a national cross-sectional study |
| title_short | Association between body mass index and respiratory symptoms in US adults: a national cross-sectional study |
| title_sort | association between body mass index and respiratory symptoms in us adults a national cross sectional study |
| url | https://doi.org/10.1038/s41598-024-51637-z |
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