Ultra-low dose of rituximab in rheumatoid arthritis: study protocol for a randomised controlled trial

Ultra-low dose of rituximab in rheumatoid arthritis: study protocol for a randomised controlled trial

Abstract Background A standard low-dosing schedule of rituximab (RTX; 2 × 500 mg or 1 × 1000 mg) is as effective for active rheumatoid arthritis (RA) as the registered dose (2 × 1000 mg). Moreover, several small uncontrolled studies suggest that even lower-dosed treatment with RTX also leads to good...

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Bibliographic Details
Main Authors: Alfons A. den Broeder, Lise M. Verhoef, Jaap Fransen, Rogier Thurlings, Bart J. F. van den Bemt, Steven Teerenstra, Nadine Boers, Nathan den Broeder, Frank H. J. van den Hoogen
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Trials
Subjects:
Rheumatoid arthritis
Dose reduction
Rituximab
Low dose
Retreatment
Randomised controlled trial
Online Access:http://link.springer.com/article/10.1186/s13063-017-2134-x

Internet

http://link.springer.com/article/10.1186/s13063-017-2134-x

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