Abnormal lipid metabolism in epidermal Langerhans cells mediates psoriasis-like dermatitis

Abnormal lipid metabolism in epidermal Langerhans cells mediates psoriasis-like dermatitis

Psoriasis is a chronic, inflammatory skin disease, frequently associated with dyslipidemia. Lipid disturbance in psoriasis affects both circulatory system and cutaneous tissue. Epidermal Langerhans cells (LCs) are tissue-resident DCs that maintain skin immune surveillance and mediate various cutaneo...

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Bibliographic Details
Main Authors: Xilin Zhang, Xiaorui Li, Yuanyuan Wang, Youdong Chen, Yijun Hu, Chunyuan Guo, Zengyang Yu, Peng Xu, Yangfeng Ding, Qing-Sheng Mi, Jianhua Wu, Jun Gu, Yuling Shi
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-07-01
Series:JCI Insight
Subjects:
Dermatology
Inflammation
Online Access:https://doi.org/10.1172/jci.insight.150223

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