How Ah Receptor Ligand Specificity Became Important in Understanding Its Physiological Function

How Ah Receptor Ligand Specificity Became Important in Understanding Its Physiological Function

Increasingly, the aryl hydrocarbon receptor (AHR) is being recognized as a sensor for endogenous and pseudo-endogenous metabolites, and in particular microbiota and host generated tryptophan metabolites. One proposed explanation for this is the role of the AHR in innate immune signaling within barri...

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Bibliographic Details
Main Authors: Iain A. Murray, Gary H. Perdew
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
AHR
Ah receptor
agonist
tryptophan
cytokines
microbiome
Online Access:https://www.mdpi.com/1422-0067/21/24/9614

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