IGF Signaling in Intervertebral Disc Health and Disease

IGF Signaling in Intervertebral Disc Health and Disease

Low back pain (LBP) is a common musculoskeletal symptom, which brings a lot of pain and economic loss to patients. One of the most common causes of LBP is intervertebral disc degeneration (IVDD). However, pathogenesis is still debated, and therapeutic options are limited. Insulin-like growth factor...

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Bibliographic Details
Main Authors: Hui Lin, Shuo Tian, Yizhong Peng, Ling Wu, Yan Xiao, Xiangcheng Qing, Zengwu Shao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
insulin-like growth factor
intervertebral disc
nucleus pulposus
degeneration
low back pain
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.817099/full

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