Impact of CYP2D6 genotype on opioid use disorder deprescription: an observational prospective study in chronic pain with sex-differences

Impact of CYP2D6 genotype on opioid use disorder deprescription: an observational prospective study in chronic pain with sex-differences

Introduction: Opioid deprescription is the process of supervised tapering and safe withdrawal when a potentially inappropriate use is detected. This represents a challenge in chronic non-cancer pain (CNCP) patients who may respond differently to the procedure. Our aim was to analyze the potential im...

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Bibliographic Details
Main Authors: Javier Muriel, Jordi Barrachina, Guillermo Del Barco, Cristian Carvajal, Mónica Escorial, César Margarit, Pura Ballester, Ana María Peiró
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
CYP2D6
sex-differences
opioid use disorder
deprescription
chronic pain
pharmacogenetics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1200430/full

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