Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis
We present a case of fatal rebound hyperkalemia in a patient with thyrotoxic periodic paralysis (TPP) treated with potassium supplementation. Although TPP is a rare hyperthyroidism-related endocrine disorder seen predominantly in men of Asian origin, the diagnosis should be considered in patients of...
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Format: | Article |
Language: | English |
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eScholarship Publishing, University of California
2010-02-01
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Series: | Western Journal of Emergency Medicine |
Subjects: | |
Online Access: | http://escholarship.org/uc/item/4s94s58c |
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author | Ahmed, Imdad Chilimuri, Sridhar |
author_facet | Ahmed, Imdad Chilimuri, Sridhar |
author_sort | Ahmed, Imdad |
collection | DOAJ |
description | We present a case of fatal rebound hyperkalemia in a patient with thyrotoxic periodic paralysis (TPP) treated with potassium supplementation. Although TPP is a rare hyperthyroidism-related endocrine disorder seen predominantly in men of Asian origin, the diagnosis should be considered in patients of non-Asian origins presenting with hypokalemia, muscle weakness or acute paralysis. The condition may present as a life threatening emergency and unfamiliarity with the disease could result in a fatal outcome. Immediate therapy with potassium chloride supplementation may foster a rapid recovery of muscle strength and prevent cardiac arrhythmias secondary to hypokalemia, but with a risk of rebound hyperkalemia. [West J Emerg Med. 2010; 11(1):57-59.] |
first_indexed | 2024-12-11T10:18:37Z |
format | Article |
id | doaj.art-40e31dca2ced457a9d75adc473db117e |
institution | Directory Open Access Journal |
issn | 1936-900X 1936-9018 |
language | English |
last_indexed | 2024-12-11T10:18:37Z |
publishDate | 2010-02-01 |
publisher | eScholarship Publishing, University of California |
record_format | Article |
series | Western Journal of Emergency Medicine |
spelling | doaj.art-40e31dca2ced457a9d75adc473db117e2022-12-22T01:11:32ZengeScholarship Publishing, University of CaliforniaWestern Journal of Emergency Medicine1936-900X1936-90182010-02-011115759Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic ParalysisAhmed, ImdadChilimuri, SridharWe present a case of fatal rebound hyperkalemia in a patient with thyrotoxic periodic paralysis (TPP) treated with potassium supplementation. Although TPP is a rare hyperthyroidism-related endocrine disorder seen predominantly in men of Asian origin, the diagnosis should be considered in patients of non-Asian origins presenting with hypokalemia, muscle weakness or acute paralysis. The condition may present as a life threatening emergency and unfamiliarity with the disease could result in a fatal outcome. Immediate therapy with potassium chloride supplementation may foster a rapid recovery of muscle strength and prevent cardiac arrhythmias secondary to hypokalemia, but with a risk of rebound hyperkalemia. [West J Emerg Med. 2010; 11(1):57-59.]http://escholarship.org/uc/item/4s94s58cThyrotoxic periodic paralysisrebound hyperkalemiamuscle weaknesshypokalemia |
spellingShingle | Ahmed, Imdad Chilimuri, Sridhar Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis Western Journal of Emergency Medicine Thyrotoxic periodic paralysis rebound hyperkalemia muscle weakness hypokalemia |
title | Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis |
title_full | Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis |
title_fullStr | Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis |
title_full_unstemmed | Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis |
title_short | Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis |
title_sort | fatal dysrhythmia following potassium replacement for hypokalemic periodic paralysis |
topic | Thyrotoxic periodic paralysis rebound hyperkalemia muscle weakness hypokalemia |
url | http://escholarship.org/uc/item/4s94s58c |
work_keys_str_mv | AT ahmedimdad fataldysrhythmiafollowingpotassiumreplacementforhypokalemicperiodicparalysis AT chilimurisridhar fataldysrhythmiafollowingpotassiumreplacementforhypokalemicperiodicparalysis |