Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis

We present a case of fatal rebound hyperkalemia in a patient with thyrotoxic periodic paralysis (TPP) treated with potassium supplementation. Although TPP is a rare hyperthyroidism-related endocrine disorder seen predominantly in men of Asian origin, the diagnosis should be considered in patients of...

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Main Authors: Ahmed, Imdad, Chilimuri, Sridhar
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2010-02-01
Series:Western Journal of Emergency Medicine
Subjects:
Online Access:http://escholarship.org/uc/item/4s94s58c
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author Ahmed, Imdad
Chilimuri, Sridhar
author_facet Ahmed, Imdad
Chilimuri, Sridhar
author_sort Ahmed, Imdad
collection DOAJ
description We present a case of fatal rebound hyperkalemia in a patient with thyrotoxic periodic paralysis (TPP) treated with potassium supplementation. Although TPP is a rare hyperthyroidism-related endocrine disorder seen predominantly in men of Asian origin, the diagnosis should be considered in patients of non-Asian origins presenting with hypokalemia, muscle weakness or acute paralysis. The condition may present as a life threatening emergency and unfamiliarity with the disease could result in a fatal outcome. Immediate therapy with potassium chloride supplementation may foster a rapid recovery of muscle strength and prevent cardiac arrhythmias secondary to hypokalemia, but with a risk of rebound hyperkalemia. [West J Emerg Med. 2010; 11(1):57-59.]
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spelling doaj.art-40e31dca2ced457a9d75adc473db117e2022-12-22T01:11:32ZengeScholarship Publishing, University of CaliforniaWestern Journal of Emergency Medicine1936-900X1936-90182010-02-011115759Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic ParalysisAhmed, ImdadChilimuri, SridharWe present a case of fatal rebound hyperkalemia in a patient with thyrotoxic periodic paralysis (TPP) treated with potassium supplementation. Although TPP is a rare hyperthyroidism-related endocrine disorder seen predominantly in men of Asian origin, the diagnosis should be considered in patients of non-Asian origins presenting with hypokalemia, muscle weakness or acute paralysis. The condition may present as a life threatening emergency and unfamiliarity with the disease could result in a fatal outcome. Immediate therapy with potassium chloride supplementation may foster a rapid recovery of muscle strength and prevent cardiac arrhythmias secondary to hypokalemia, but with a risk of rebound hyperkalemia. [West J Emerg Med. 2010; 11(1):57-59.]http://escholarship.org/uc/item/4s94s58cThyrotoxic periodic paralysisrebound hyperkalemiamuscle weaknesshypokalemia
spellingShingle Ahmed, Imdad
Chilimuri, Sridhar
Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis
Western Journal of Emergency Medicine
Thyrotoxic periodic paralysis
rebound hyperkalemia
muscle weakness
hypokalemia
title Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis
title_full Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis
title_fullStr Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis
title_full_unstemmed Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis
title_short Fatal Dysrhythmia Following Potassium Replacement for Hypokalemic Periodic Paralysis
title_sort fatal dysrhythmia following potassium replacement for hypokalemic periodic paralysis
topic Thyrotoxic periodic paralysis
rebound hyperkalemia
muscle weakness
hypokalemia
url http://escholarship.org/uc/item/4s94s58c
work_keys_str_mv AT ahmedimdad fataldysrhythmiafollowingpotassiumreplacementforhypokalemicperiodicparalysis
AT chilimurisridhar fataldysrhythmiafollowingpotassiumreplacementforhypokalemicperiodicparalysis