Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort study
Background: Ovarian cancer is one of the deadliest cancers, as it is the seventh most prevalent type of cancer in women worldwide. Objectives: This study aimed to assess the feasibility and efficacy of diagnostic laparoscopy in predicting optimum respectability in ovarian cancer cases. Patients an...
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| Format: | Article |
| Language: | English |
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South Valley University, Faculty of Medicine
2023-01-01
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| Series: | SVU - International Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://svuijm.journals.ekb.eg/article_259034.html |
| _version_ | 1828034522278526976 |
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| author | Mohammed Abdelrahman Ahmed Magdy Mahmoud* Abdelnaser Abd Elgaber Ali Hanan Mahmoud Fayed Mostafa Mohammed Khodary |
| author_facet | Mohammed Abdelrahman Ahmed Magdy Mahmoud* Abdelnaser Abd Elgaber Ali Hanan Mahmoud Fayed Mostafa Mohammed Khodary |
| author_sort | Mohammed Abdelrahman |
| collection | DOAJ |
| description | Background: Ovarian cancer is one of the deadliest cancers, as it is the seventh most prevalent type of cancer in women worldwide.
Objectives: This study aimed to assess the feasibility and efficacy of diagnostic laparoscopy in predicting optimum respectability in ovarian cancer cases.
Patients and methods: it was a prospective cohort study, including 38 ovarian cancer cases. The duration of the study ranged from 6-24 months. A receiver-operating characteristic (ROC) curve was constructed to assess the diagnostic ability of laparoscopy. Overall survival (OS), disease-free survival (DFS), and recurrence-free survival (RFS) were calculated using the Kaplan-Meier method.
Results: of the studied patients, 30 (78.9%) were diagnosed with stage III, and 6.5% of surgically resectable cases were found to be unresectable at laparoscopy, with a 93.5% true positive. To assess resectability, the diagnostic utility revealed that laparoscopy had 93.6% sensitivity, 100% specificity, 77.8% NPV, and 100% PPV with an accuracy of 94.7%.Serous cystadenocarcinoma was the most common histopathology type in 24(63.15%) patients. The OS during the observation period was 26.8 months ±1.1 (CI: 24.6–29.0). The estimated DFS was 9.15 months for all patients, 10 months for 25% of patients, and 8 months for 75% of patients. The RFS was 9.56 months.
Conclusion: Diagnostic laparoscopy has effective feasibility and great efficacy when added to the conventional initial diagnostic workup in predicting optimum resectability of ovarian cancer. |
| first_indexed | 2024-04-10T15:34:19Z |
| format | Article |
| id | doaj.art-40e5076f49f148a890d851c14d4547f0 |
| institution | Directory Open Access Journal |
| issn | 2735-427X 2636-3402 |
| language | English |
| last_indexed | 2024-04-10T15:34:19Z |
| publishDate | 2023-01-01 |
| publisher | South Valley University, Faculty of Medicine |
| record_format | Article |
| series | SVU - International Journal of Medical Sciences |
| spelling | doaj.art-40e5076f49f148a890d851c14d4547f02023-02-13T07:34:30ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022023-01-0161 28329010.21608/SVUIJM.2022.157090.1386 Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort studyMohammed Abdelrahman0 Ahmed Magdy Mahmoud*1 Abdelnaser Abd Elgaber Ali2Hanan Mahmoud Fayed3Mostafa Mohammed Khodary4Department of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, Egypt.Department of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, EgyptDepartment of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, EgyptDepartment of Chemical and Clinical pathology, Faculty of Medicine, South Valley University, Qena, EgyptDepartment of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, EgyptBackground: Ovarian cancer is one of the deadliest cancers, as it is the seventh most prevalent type of cancer in women worldwide. Objectives: This study aimed to assess the feasibility and efficacy of diagnostic laparoscopy in predicting optimum respectability in ovarian cancer cases. Patients and methods: it was a prospective cohort study, including 38 ovarian cancer cases. The duration of the study ranged from 6-24 months. A receiver-operating characteristic (ROC) curve was constructed to assess the diagnostic ability of laparoscopy. Overall survival (OS), disease-free survival (DFS), and recurrence-free survival (RFS) were calculated using the Kaplan-Meier method. Results: of the studied patients, 30 (78.9%) were diagnosed with stage III, and 6.5% of surgically resectable cases were found to be unresectable at laparoscopy, with a 93.5% true positive. To assess resectability, the diagnostic utility revealed that laparoscopy had 93.6% sensitivity, 100% specificity, 77.8% NPV, and 100% PPV with an accuracy of 94.7%.Serous cystadenocarcinoma was the most common histopathology type in 24(63.15%) patients. The OS during the observation period was 26.8 months ±1.1 (CI: 24.6–29.0). The estimated DFS was 9.15 months for all patients, 10 months for 25% of patients, and 8 months for 75% of patients. The RFS was 9.56 months. Conclusion: Diagnostic laparoscopy has effective feasibility and great efficacy when added to the conventional initial diagnostic workup in predicting optimum resectability of ovarian cancer.https://svuijm.journals.ekb.eg/article_259034.htmllaparoscopy; adjuvant chemotherapy; ovarian neoplasms; ovarian pathology; ovarian surgery |
| spellingShingle | Mohammed Abdelrahman Ahmed Magdy Mahmoud* Abdelnaser Abd Elgaber Ali Hanan Mahmoud Fayed Mostafa Mohammed Khodary Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort study SVU - International Journal of Medical Sciences laparoscopy; adjuvant chemotherapy; ovarian neoplasms; ovarian pathology; ovarian surgery |
| title | Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort study |
| title_full | Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort study |
| title_fullStr | Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort study |
| title_full_unstemmed | Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort study |
| title_short | Feasibility and ability of laparoscopy to predict respectability in ovarian cancer: A cohort study |
| title_sort | feasibility and ability of laparoscopy to predict respectability in ovarian cancer a cohort study |
| topic | laparoscopy; adjuvant chemotherapy; ovarian neoplasms; ovarian pathology; ovarian surgery |
| url | https://svuijm.journals.ekb.eg/article_259034.html |
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