Functional production of clostridial circularin A in Lactococcus lactis NZ9000 and mutational analysis of its aromatic and cationic residues

Functional production of clostridial circularin A in Lactococcus lactis NZ9000 and mutational analysis of its aromatic and cationic residues

Circular bacteriocins, also known as bacterial head-to-tail cyclized peptides, are a subgroup of ribosomally synthesized and post-translationally modified peptides (RiPPs). Compared with their conventional linear counterparts, circular bacteriocins are highly stable over a broad temperature and pH r...

Full description

Bibliographic Details
Main Authors: Fangfang Liu, Auke J. van Heel, Jingqi Chen, Oscar P. Kuipers
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
RiPPs
circularin A
Lactococcus lactis
antimicrobial activity
biosynthesis
mutagenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1026290/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1026290/full

Similar Items