Chronic Effects of Apelin on Cardiovascular Regulation and Angiotensin II-Induced Hypertension

Chronic Effects of Apelin on Cardiovascular Regulation and Angiotensin II-Induced Hypertension

Apelin, by stimulation of APJ receptors, induces transient blood pressure (BP) reduction and positive inotropic effects. APJ receptors share high homology with the Ang II type 1 receptor; thus, apelin was proposed to play a protective role in cardiovascular disease by antagonizing the actions of Ang...

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Bibliographic Details
Main Authors: Qi Zhang, Yue Shen, Sayeman Islam Niloy, Stephen T. O'Rourke, Chengwen Sun
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceuticals
Subjects:
apelin
APJ receptor
blood pressure
hypertension
angiotensin II
Online Access:https://www.mdpi.com/1424-8247/16/4/600

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