Higher gravidity and parity are associated with increased prevalence of metabolic syndrome among rural Bangladeshi women.

BACKGROUND: Parity increases the risk for coronary heart disease; however, its association with metabolic syndrome among women in low-income countries is still unknown. OBJECTIVE: This study investigates the association between parity or gravidity and metabolic syndrome in rural Bangladeshi women. M...

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Bibliographic Details
Main Authors: Shamima Akter, Subrina Jesmin, Md Mizanur Rahman, Md Majedul Islam, Most Tanzila Khatun, Naoto Yamaguchi, Hidechika Akashi, Taro Mizutani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3732242?pdf=render
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Summary:BACKGROUND: Parity increases the risk for coronary heart disease; however, its association with metabolic syndrome among women in low-income countries is still unknown. OBJECTIVE: This study investigates the association between parity or gravidity and metabolic syndrome in rural Bangladeshi women. METHODS: A cross-sectional study was conducted in 1,219 women aged 15-75 years from rural Bangladesh. Metabolic syndrome was defined according to the standard NCEP-ATP III criteria. Logistic regression was used to estimate the association between parity and gravidity and metabolic syndrome, with adjustment of potential confounding variables. RESULTS: Subjects with the highest gravidity (> = 4) had 1.66 times higher odds of having metabolic syndrome compared to those in the lowest gravidity (0-1) (P trend = 0.02). A similar association was found between parity and metabolic syndrome (P(trend) = 0.04), i.e., subjects in the highest parity (> = 4) had 1.65 times higher odds of having metabolic syndrome compared to those in the lowest parity (0-1). This positive association of parity and gravidity with metabolic syndrome was confined to pre-menopausal women (P(trend) <0.01). Among the components of metabolic syndrome only high blood pressure showed positive association with parity and gravidity (P(trend) = 0.01 and <0.001). Neither Parity nor gravidity was appreciably associated with other components of metabolic syndrome. CONCLUSIONS: Multi parity or gravidity may be a risk factor for metabolic syndrome.
ISSN:1932-6203