Lycopene prevents non-alcoholic fatty liver disease through regulating hepatic NF-κB/NLRP3 inflammasome pathway and intestinal microbiota in mice fed with high-fat and high-fructose diet

Lycopene prevents non-alcoholic fatty liver disease through regulating hepatic NF-κB/NLRP3 inflammasome pathway and intestinal microbiota in mice fed with high-fat and high-fructose diet

Lycopene (LY) belongs to carotenoids and is abundant in red fruits and vegetables. Several previous studies suggested that LY is beneficial for ameliorating non-alcoholic fatty liver disease (NAFLD), while the potential mechanisms are unclear. The present study aimed to clarify the potential mechani...

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Bibliographic Details
Main Authors: Xiang Gao, Xia Zhao, Min Liu, Huimin Zhao, Yongye Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Nutrition
Subjects:
lycopene
NLRP3
nonalcoholic fatty liver disease
intestinal microbiota
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1120254/full

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