Genistein Sensitizes Human Cholangiocarcinoma Cell Lines to Be Susceptible to Natural Killer Cells

Genistein Sensitizes Human Cholangiocarcinoma Cell Lines to Be Susceptible to Natural Killer Cells

Cholangiocarcinoma (CCA) is a lethal bile duct cancer, which has poor treatment outcomes due to its high resistance to chemotherapy and cancer recurrence. Activation of aberrant anti-apoptotic signaling pathway has been reported to be a mechanism of chemoresistance and immune escape of CCA. Therefor...

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Bibliographic Details
Main Authors: Chutipa Chiawpanit, Suthida Panwong, Nunghathai Sawasdee, Pa-thai Yenchitsomanus, Aussara Panya
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biology
Subjects:
cholangiocarcinoma
genistein
sensitization
apoptosis
death receptors
NK-92 cells
Online Access:https://www.mdpi.com/2079-7737/11/8/1098

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