Lysine Acetylome Study of Human Hepatocellular Carcinoma Tissues for Biomarkers and Therapeutic Targets Discovery

Lysine Acetylome Study of Human Hepatocellular Carcinoma Tissues for Biomarkers and Therapeutic Targets Discovery

Lysine acetylation is a vital post-translational modification (PTM) of proteins, which plays an important role in cancer development. In healthy human liver tissues, multiple non-histone proteins were identified with acetylation modification, however, the role of acetylated proteins in hepatocellula...

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Bibliographic Details
Main Authors: Qianwei Zhao, Zhendong Zhang, Jinxia Li, Fang Xu, Bingxia Zhang, Mengduan Liu, Yixian Liu, Huiping Chen, Junxia Yang, Jintao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
hepatocellular carcinoma
lysine acetylation
non-histone proteins
sirtuins
biomarker candidates
drug discovery
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.572663/full

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