Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma
INTRODUCTION[|]To assess the levels of red cell distribution width (RDW) in patients with pseudoexfoliation syndrome (PEX) and to compare the RDW values of patients with PEX, PEX glaucoma (PXG), and healthy controls.[¤]METHODS[|]In total, 45 patients with PEX, 14 patients with PXG, and 43 age- and s...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2018-12-01
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| Series: | Beyoglu Eye Journal |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-53825 |
| _version_ | 1797922513837096960 |
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| author | Bengi Ece Kurtul Emrah Utku Kabataş |
| author_facet | Bengi Ece Kurtul Emrah Utku Kabataş |
| author_sort | Bengi Ece Kurtul |
| collection | DOAJ |
| description | INTRODUCTION[|]To assess the levels of red cell distribution width (RDW) in patients with pseudoexfoliation syndrome (PEX) and to compare the RDW values of patients with PEX, PEX glaucoma (PXG), and healthy controls.[¤]METHODS[|]In total, 45 patients with PEX, 14 patients with PXG, and 43 age- and sex-matchd healthy control subjects were enrolled in this retrospective study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 1 h of blood collection.[¤]RESULTS[|]RDW levels were significantly higher in patients with PEX and PXG than in those with controls (p = 0.037 and p < 0.001, respectively). Also, a significant difference was found in RDW values between PXG and PEX groups (p = 0.028). RDW levels were gradually increased from control group to PXG group (p < 0.001 for one-way ANOVA). Multivariate logistic regression analysis revealed that RDW was independently associated with the presence of PEX/PXG (odds ratio 1.698, 95% confidence interval 1.077-2.677, p = 0.023).[¤]DISCUSSION AND CONCLUSION[|]The present study for the first time provides evidence that RDW may be an useful marker for predicting the presence of PEX and progression to PXG.[¤] |
| first_indexed | 2024-04-10T14:32:37Z |
| format | Article |
| id | doaj.art-4104b82f58a74736bd1e007b91e37687 |
| institution | Directory Open Access Journal |
| issn | 2587-0394 |
| language | English |
| last_indexed | 2024-04-10T14:32:37Z |
| publishDate | 2018-12-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Beyoglu Eye Journal |
| spelling | doaj.art-4104b82f58a74736bd1e007b91e376872023-02-15T16:08:42ZengKARE PublishingBeyoglu Eye Journal2587-03942018-12-013312212710.14744/bej.2018.53825BEJ-53825Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucomaBengi Ece Kurtul0Emrah Utku Kabataş1Department of Ophthalmology, Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital, Ankara, TurkeyDepartment of Ophthalmology, Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital, Ankara, TurkeyINTRODUCTION[|]To assess the levels of red cell distribution width (RDW) in patients with pseudoexfoliation syndrome (PEX) and to compare the RDW values of patients with PEX, PEX glaucoma (PXG), and healthy controls.[¤]METHODS[|]In total, 45 patients with PEX, 14 patients with PXG, and 43 age- and sex-matchd healthy control subjects were enrolled in this retrospective study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 1 h of blood collection.[¤]RESULTS[|]RDW levels were significantly higher in patients with PEX and PXG than in those with controls (p = 0.037 and p < 0.001, respectively). Also, a significant difference was found in RDW values between PXG and PEX groups (p = 0.028). RDW levels were gradually increased from control group to PXG group (p < 0.001 for one-way ANOVA). Multivariate logistic regression analysis revealed that RDW was independently associated with the presence of PEX/PXG (odds ratio 1.698, 95% confidence interval 1.077-2.677, p = 0.023).[¤]DISCUSSION AND CONCLUSION[|]The present study for the first time provides evidence that RDW may be an useful marker for predicting the presence of PEX and progression to PXG.[¤]https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-53825pseudoexfoliation syndromepseudoexfoliation glaucomared cell distribution widthinflammation |
| spellingShingle | Bengi Ece Kurtul Emrah Utku Kabataş Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma Beyoglu Eye Journal pseudoexfoliation syndrome pseudoexfoliation glaucoma red cell distribution width inflammation |
| title | Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma |
| title_full | Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma |
| title_fullStr | Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma |
| title_full_unstemmed | Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma |
| title_short | Elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma |
| title_sort | elevated red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma |
| topic | pseudoexfoliation syndrome pseudoexfoliation glaucoma red cell distribution width inflammation |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=beyoglu&un=BEJ-53825 |
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