Pharmacological management of acute bronchiolitis
Melvin Wright, Charles J Mullett, Giovanni PiedimonteDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV, USAAbstract: This article reviews the current knowledge base related to the pharmacological treatments for acute bronchiolitis. Bronchiolitis is a common lower...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2008-11-01
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| Series: | Therapeutics and Clinical Risk Management |
| Online Access: | http://www.dovepress.com/pharmacological-management-of-acute-bronchiolitis-a2545 |
| _version_ | 1818461971393019904 |
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| author | Melvin Wright Charles J Mullett Giovanni Piedimonte |
| author_facet | Melvin Wright Charles J Mullett Giovanni Piedimonte |
| author_sort | Melvin Wright |
| collection | DOAJ |
| description | Melvin Wright, Charles J Mullett, Giovanni PiedimonteDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV, USAAbstract: This article reviews the current knowledge base related to the pharmacological treatments for acute bronchiolitis. Bronchiolitis is a common lower respiratory illness affecting infants worldwide. The mainstays of therapy include airway support, supplemental oxygen, and support of fluids and nutrition. Frequently tried pharmacological interventions, such as ribavirin, nebulized bronchodilators, and systemic corticosteroids, have not been proven to benefit patients with bronchiolitis. Antibiotics do not improve the clinical course of patients with bronchiolitis, and should be used only in those patients with proven concurrent bacterial infection. Exogenous surfactant and heliox therapy also cannot be recommended for routine use, but surfactant replacement holds promise and should be further studied.Keywords: bronchiolitis, respiratory syncytial virus, pharmacological, therapy, interventions |
| first_indexed | 2024-12-14T23:54:37Z |
| format | Article |
| id | doaj.art-410818a212694554be1bac03e97bbe3f |
| institution | Directory Open Access Journal |
| issn | 1176-6336 1178-203X |
| language | English |
| last_indexed | 2024-12-14T23:54:37Z |
| publishDate | 2008-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Therapeutics and Clinical Risk Management |
| spelling | doaj.art-410818a212694554be1bac03e97bbe3f2022-12-21T22:43:08ZengDove Medical PressTherapeutics and Clinical Risk Management1176-63361178-203X2008-11-012008Issue 5895903Pharmacological management of acute bronchiolitisMelvin WrightCharles J MullettGiovanni PiedimonteMelvin Wright, Charles J Mullett, Giovanni PiedimonteDepartment of Pediatrics, West Virginia University School of Medicine, Morgantown, WV, USAAbstract: This article reviews the current knowledge base related to the pharmacological treatments for acute bronchiolitis. Bronchiolitis is a common lower respiratory illness affecting infants worldwide. The mainstays of therapy include airway support, supplemental oxygen, and support of fluids and nutrition. Frequently tried pharmacological interventions, such as ribavirin, nebulized bronchodilators, and systemic corticosteroids, have not been proven to benefit patients with bronchiolitis. Antibiotics do not improve the clinical course of patients with bronchiolitis, and should be used only in those patients with proven concurrent bacterial infection. Exogenous surfactant and heliox therapy also cannot be recommended for routine use, but surfactant replacement holds promise and should be further studied.Keywords: bronchiolitis, respiratory syncytial virus, pharmacological, therapy, interventionshttp://www.dovepress.com/pharmacological-management-of-acute-bronchiolitis-a2545 |
| spellingShingle | Melvin Wright Charles J Mullett Giovanni Piedimonte Pharmacological management of acute bronchiolitis Therapeutics and Clinical Risk Management |
| title | Pharmacological management of acute bronchiolitis |
| title_full | Pharmacological management of acute bronchiolitis |
| title_fullStr | Pharmacological management of acute bronchiolitis |
| title_full_unstemmed | Pharmacological management of acute bronchiolitis |
| title_short | Pharmacological management of acute bronchiolitis |
| title_sort | pharmacological management of acute bronchiolitis |
| url | http://www.dovepress.com/pharmacological-management-of-acute-bronchiolitis-a2545 |
| work_keys_str_mv | AT melvinwright pharmacologicalmanagementofacutebronchiolitis AT charlesjmullett pharmacologicalmanagementofacutebronchiolitis AT giovannipiedimonte pharmacologicalmanagementofacutebronchiolitis |