Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resin

Background: Ferula assa-foetida is an endemic medicinal plant of Iran. Its oleo-gum resin or assafoetida gum (AG) is an important herbal product whose standardization is important to ensure effectiveness and safety. Objective: Due to the lack of accurate and complete data about Iranian AG, the objec...

Full description

Bibliographic Details
Main Authors: Fatemeh Alijaniha, Fatemeh Emadi, Mohsen Naseri, Zahra Bahaeddin, Najmeh Dehparvar
Format: Article
Language:English
Published: Institue of Medicinal Plants, ACECR 2023-03-01
Series:Journal of Medicinal Plants
Subjects:
Online Access:http://jmp.ir/article-1-3463-en.pdf
_version_ 1797773135379955712
author Fatemeh Alijaniha
Fatemeh Emadi
Mohsen Naseri
Zahra Bahaeddin
Najmeh Dehparvar
author_facet Fatemeh Alijaniha
Fatemeh Emadi
Mohsen Naseri
Zahra Bahaeddin
Najmeh Dehparvar
author_sort Fatemeh Alijaniha
collection DOAJ
description Background: Ferula assa-foetida is an endemic medicinal plant of Iran. Its oleo-gum resin or assafoetida gum (AG) is an important herbal product whose standardization is important to ensure effectiveness and safety. Objective: Due to the lack of accurate and complete data about Iranian AG, the objective of this study is to extend the available knowledge by reporting some physicochemical and phytochemical properties of an Iranian AG sample. Methods: Organoleptic properties were determined by sensory evaluation. Total ash, acid-insoluble ash, dry residue as well as total phenolic and flavonoid content were measured by accepted methods to determine some physicochemical and phytochemical properties of AG. Analysis of its essential oil by GC/MS as well as microbial load assessment were performed. Results: The AG was a yellowish brown mass with a sulfur-like pungent odor similar to garlic, with total ash and acid-insoluble ash of 2.83 % and 2.06 %, respectively, and a dry residue of 3.43 %. Total phenol content was 4.15 ± 0.26 mg gallic acid equivalent/g in dry AG. (E)-1-Propenyl sec-butyl disulphide, (Z)-1-propenyl sec-butyl disulphide, and 2,4-thiazelidinedione were the major essential oil component of this oleo-gum resin. Microbial load was in acceptable range according to Pharmacopeia. Conclusion: The current findings provide data on some of the physicochemical and phytochemical properties of Iranian AG which is applicable for completing current knowledge. Although more information is needed for establishing Iranian AG standardization criteria, which will be obtained from more extensive researches.
first_indexed 2024-03-12T22:00:55Z
format Article
id doaj.art-410d631b10ec40888d35e6961084ad0e
institution Directory Open Access Journal
issn 2717-204X
2717-2058
language English
last_indexed 2024-03-12T22:00:55Z
publishDate 2023-03-01
publisher Institue of Medicinal Plants, ACECR
record_format Article
series Journal of Medicinal Plants
spelling doaj.art-410d631b10ec40888d35e6961084ad0e2023-07-25T07:23:11ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582023-03-0122858997Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resinFatemeh Alijaniha0Fatemeh Emadi1Mohsen Naseri2Zahra Bahaeddin3Najmeh Dehparvar4 Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran; School of Persian Medicine, Shahed University, Tehran, Iran Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran; School of Persian Medicine, Shahed University, Tehran, Iran Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran; School of Persian Medicine, Shahed University, Tehran, Iran Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran; School of Persian Medicine, Shahed University, Tehran, Iran School of Persian Medicine, Shahed University, Tehran, Iran Background: Ferula assa-foetida is an endemic medicinal plant of Iran. Its oleo-gum resin or assafoetida gum (AG) is an important herbal product whose standardization is important to ensure effectiveness and safety. Objective: Due to the lack of accurate and complete data about Iranian AG, the objective of this study is to extend the available knowledge by reporting some physicochemical and phytochemical properties of an Iranian AG sample. Methods: Organoleptic properties were determined by sensory evaluation. Total ash, acid-insoluble ash, dry residue as well as total phenolic and flavonoid content were measured by accepted methods to determine some physicochemical and phytochemical properties of AG. Analysis of its essential oil by GC/MS as well as microbial load assessment were performed. Results: The AG was a yellowish brown mass with a sulfur-like pungent odor similar to garlic, with total ash and acid-insoluble ash of 2.83 % and 2.06 %, respectively, and a dry residue of 3.43 %. Total phenol content was 4.15 ± 0.26 mg gallic acid equivalent/g in dry AG. (E)-1-Propenyl sec-butyl disulphide, (Z)-1-propenyl sec-butyl disulphide, and 2,4-thiazelidinedione were the major essential oil component of this oleo-gum resin. Microbial load was in acceptable range according to Pharmacopeia. Conclusion: The current findings provide data on some of the physicochemical and phytochemical properties of Iranian AG which is applicable for completing current knowledge. Although more information is needed for establishing Iranian AG standardization criteria, which will be obtained from more extensive researches.http://jmp.ir/article-1-3463-en.pdfferula assa-foetida l.iranphysicochemicalphytochemicalstandardizationoleo-gum resin
spellingShingle Fatemeh Alijaniha
Fatemeh Emadi
Mohsen Naseri
Zahra Bahaeddin
Najmeh Dehparvar
Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resin
Journal of Medicinal Plants
ferula assa-foetida l.
iran
physicochemical
phytochemical
standardization
oleo-gum resin
title Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resin
title_full Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resin
title_fullStr Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resin
title_full_unstemmed Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resin
title_short Some physicochemical and phytochemical characteristics of Iranian Ferula assa-foetida L. oleo-gum resin
title_sort some physicochemical and phytochemical characteristics of iranian ferula assa foetida l oleo gum resin
topic ferula assa-foetida l.
iran
physicochemical
phytochemical
standardization
oleo-gum resin
url http://jmp.ir/article-1-3463-en.pdf
work_keys_str_mv AT fatemehalijaniha somephysicochemicalandphytochemicalcharacteristicsofiranianferulaassafoetidaloleogumresin
AT fatemehemadi somephysicochemicalandphytochemicalcharacteristicsofiranianferulaassafoetidaloleogumresin
AT mohsennaseri somephysicochemicalandphytochemicalcharacteristicsofiranianferulaassafoetidaloleogumresin
AT zahrabahaeddin somephysicochemicalandphytochemicalcharacteristicsofiranianferulaassafoetidaloleogumresin
AT najmehdehparvar somephysicochemicalandphytochemicalcharacteristicsofiranianferulaassafoetidaloleogumresin