Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysis
Abstract Background This meta‐analysis of randomized controlled trials (RCTs) compared long‐term adverse clinical outcomes of percutaneous coronary intervention (PCI) in insulin‐treated diabetes mellitus (ITDM) and non‐ITDM patients. Methods This is a meta‐analysis study. The PubMed and Embase datab...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-09-01
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| Series: | Annals of Noninvasive Electrocardiology |
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| Online Access: | https://doi.org/10.1111/anec.12953 |
| _version_ | 1798035835387379712 |
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| author | Ying Ge Daikun He Yiru Shao Lina Wang Wei Yan |
| author_facet | Ying Ge Daikun He Yiru Shao Lina Wang Wei Yan |
| author_sort | Ying Ge |
| collection | DOAJ |
| description | Abstract Background This meta‐analysis of randomized controlled trials (RCTs) compared long‐term adverse clinical outcomes of percutaneous coronary intervention (PCI) in insulin‐treated diabetes mellitus (ITDM) and non‐ITDM patients. Methods This is a meta‐analysis study. The PubMed and Embase databases were searched for articles on long‐term adverse clinical outcomes of PCI in ITDM and non‐ITDM patients. The risk ratios (RR) and 95% confidence intervals (CI) were calculated. Results A total of 11 related RCTs involving 8853 DM patients were included. Compared with non‐ITDM patients, ITDM patients had significantly higher all‐cause mortality (ACM) (RR = 1.52, 95% CI: 1.25–1.85, pheterogeneity = .689, I2 = 0%), major adverse cardiac and cerebrovascular events (MACCE) (RR = 1.35, 95% CI: 1.18–1.55, pheterogeneity = .57, I2 = 0%), myocardial infarction (MI) (RR = 1.41, 95% CI: 1.16–1.72, pheterogeneity = .962, I2 = 0%), and stent thrombosis (ST) (RR = 1.75, 95% CI: 1.23–2.48, pheterogeneity = .159, I2 = 32.4%). No significant difference was found in the target lesion revascularization (TLR) and target vessel revascularization (TVR) between the ITDM and non‐ITDM groups. Conclusions The results showed that ITDM patients had significantly higher ACM, MACCE, MI, and ST, compared with non‐ITDM patients. |
| first_indexed | 2024-04-11T21:03:48Z |
| format | Article |
| id | doaj.art-410e581324fb46f38701a493210ed926 |
| institution | Directory Open Access Journal |
| issn | 1082-720X 1542-474X |
| language | English |
| last_indexed | 2024-04-11T21:03:48Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Annals of Noninvasive Electrocardiology |
| spelling | doaj.art-410e581324fb46f38701a493210ed9262022-12-22T04:03:24ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2022-09-01275n/an/a10.1111/anec.12953Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysisYing Ge0Daikun He1Yiru Shao2Lina Wang3Wei Yan4Department of General Practice Jinshan Hospital of Fudan University Shanghai ChinaDepartment of General Practice Jinshan Hospital of Fudan University Shanghai ChinaCenter of Emergency & Intensive Care Unit Jinshan Hospital of Fudan University Shanghai ChinaDepartment of General Practice Jinshan Hospital of Fudan University Shanghai ChinaDepartment of General Practice Jinshan Hospital of Fudan University Shanghai ChinaAbstract Background This meta‐analysis of randomized controlled trials (RCTs) compared long‐term adverse clinical outcomes of percutaneous coronary intervention (PCI) in insulin‐treated diabetes mellitus (ITDM) and non‐ITDM patients. Methods This is a meta‐analysis study. The PubMed and Embase databases were searched for articles on long‐term adverse clinical outcomes of PCI in ITDM and non‐ITDM patients. The risk ratios (RR) and 95% confidence intervals (CI) were calculated. Results A total of 11 related RCTs involving 8853 DM patients were included. Compared with non‐ITDM patients, ITDM patients had significantly higher all‐cause mortality (ACM) (RR = 1.52, 95% CI: 1.25–1.85, pheterogeneity = .689, I2 = 0%), major adverse cardiac and cerebrovascular events (MACCE) (RR = 1.35, 95% CI: 1.18–1.55, pheterogeneity = .57, I2 = 0%), myocardial infarction (MI) (RR = 1.41, 95% CI: 1.16–1.72, pheterogeneity = .962, I2 = 0%), and stent thrombosis (ST) (RR = 1.75, 95% CI: 1.23–2.48, pheterogeneity = .159, I2 = 32.4%). No significant difference was found in the target lesion revascularization (TLR) and target vessel revascularization (TVR) between the ITDM and non‐ITDM groups. Conclusions The results showed that ITDM patients had significantly higher ACM, MACCE, MI, and ST, compared with non‐ITDM patients.https://doi.org/10.1111/anec.12953diabetes mellitusinsulinmeta‐analysispercutaneous coronary interventionsystematic review |
| spellingShingle | Ying Ge Daikun He Yiru Shao Lina Wang Wei Yan Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysis Annals of Noninvasive Electrocardiology diabetes mellitus insulin meta‐analysis percutaneous coronary intervention systematic review |
| title | Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysis |
| title_full | Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysis |
| title_fullStr | Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysis |
| title_full_unstemmed | Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysis |
| title_short | Percutaneous coronary intervention in insulin‐treated diabetic patients: A meta‐analysis |
| title_sort | percutaneous coronary intervention in insulin treated diabetic patients a meta analysis |
| topic | diabetes mellitus insulin meta‐analysis percutaneous coronary intervention systematic review |
| url | https://doi.org/10.1111/anec.12953 |
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