Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung
Pseudomonas aeruginosa displays substantial genetic diversification across sub-compartments in cystic fibrosis (CF) lungs. Here, Kordes et al. show that, despite genetic variation, the ex vivo transcriptional profiles of P. aeruginosa populations are similar across five different areas in an explant...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-11414-3 |
| _version_ | 1818841978537771008 |
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| author | Adrian Kordes Matthias Preusse Sven D. Willger Peter Braubach Danny Jonigk Axel Haverich Gregor Warnecke Susanne Häussler |
| author_facet | Adrian Kordes Matthias Preusse Sven D. Willger Peter Braubach Danny Jonigk Axel Haverich Gregor Warnecke Susanne Häussler |
| author_sort | Adrian Kordes |
| collection | DOAJ |
| description | Pseudomonas aeruginosa displays substantial genetic diversification across sub-compartments in cystic fibrosis (CF) lungs. Here, Kordes et al. show that, despite genetic variation, the ex vivo transcriptional profiles of P. aeruginosa populations are similar across five different areas in an explanted CF lung. |
| first_indexed | 2024-12-19T04:34:40Z |
| format | Article |
| id | doaj.art-41109456e2284ab3b88bf9009b20cd58 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T04:34:40Z |
| publishDate | 2019-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-41109456e2284ab3b88bf9009b20cd582022-12-21T20:35:48ZengNature PortfolioNature Communications2041-17232019-07-0110111010.1038/s41467-019-11414-3Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lungAdrian Kordes0Matthias Preusse1Sven D. Willger2Peter Braubach3Danny Jonigk4Axel Haverich5Gregor Warnecke6Susanne Häussler7Institute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection ResearchInstitute for Molecular Bacteriology, Helmholtz Centre for Infection ResearchInstitute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection ResearchInstitute of Pathology, Hannover Medical SchoolInstitute of Pathology, Hannover Medical SchoolBiomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (Deutsches Zentrum für Lungenforschung [DZL])Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (Deutsches Zentrum für Lungenforschung [DZL])Institute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection ResearchPseudomonas aeruginosa displays substantial genetic diversification across sub-compartments in cystic fibrosis (CF) lungs. Here, Kordes et al. show that, despite genetic variation, the ex vivo transcriptional profiles of P. aeruginosa populations are similar across five different areas in an explanted CF lung.https://doi.org/10.1038/s41467-019-11414-3 |
| spellingShingle | Adrian Kordes Matthias Preusse Sven D. Willger Peter Braubach Danny Jonigk Axel Haverich Gregor Warnecke Susanne Häussler Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung Nature Communications |
| title | Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung |
| title_full | Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung |
| title_fullStr | Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung |
| title_full_unstemmed | Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung |
| title_short | Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung |
| title_sort | genetically diverse pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung |
| url | https://doi.org/10.1038/s41467-019-11414-3 |
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