Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study
Two methods are currently available for left atrial (LA) strain measurement by speckle tracking echocardiography, with two different reference timings for starting the analysis: QRS (QRS-LASr) and P wave (P-LASr). The aim of MASCOT HIT study was to define which of the two was more reproducible, more...
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| Language: | English |
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MDPI AG
2020-11-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/10/11/946 |
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| author | Matteo Cameli Marcelo Haertel Miglioranza Julien Magne Giulia Elena Mandoli Giovanni Benfari Roberta Ancona Gerolamo Sibilio Vlatka Reskovic Luksic Dosen Dejan Leonardo Griseli Caroline M. Van De Heyning Philippe Mortelmans Blazej Michalski Karolina Kupczynska Giovanna Di Giannuario Fiorella Devito Raluca Dulgheru Federica Ilardi Alessandro Salustri Galal Abushahba Doralisa Morrone Iacopo Fabiani Martin Penicka Asim Katbeh Giuseppe Sammarco Roberta Esposito Ciro Santoro Maria Concetta Pastore Salvatore Comenale Pinto Artem Kalinin Žanna Pičkure Katja Ažman Juvan Anja Zupan Mežnar Augustine Coisne Amandine Coppin Mihaela Maria Opris Dan Octavian Nistor Riitta Paakkanen Tor Biering-Sørensen Flemming Javier Olsen Tomas Lapinskas Jolanta Justina Vaškelyté Laura Galian-Gay Guillem Casas Andreea Iulia Motoc Constantinos Hristou Papadopoulos Savvas Loizos Gergely Ágoston Istvan Szabó Krasimira Hristova Svetlin Netkov Tsonev Elena Galli Dragos Vinereanu Sorina Mihaila Baldea Denisa Muraru Sergio Mondillo Erwan Donal Maurizio Galderisi Bernard Cosyns Thor Edvardsen Bogdan A. Popescu |
| author_facet | Matteo Cameli Marcelo Haertel Miglioranza Julien Magne Giulia Elena Mandoli Giovanni Benfari Roberta Ancona Gerolamo Sibilio Vlatka Reskovic Luksic Dosen Dejan Leonardo Griseli Caroline M. Van De Heyning Philippe Mortelmans Blazej Michalski Karolina Kupczynska Giovanna Di Giannuario Fiorella Devito Raluca Dulgheru Federica Ilardi Alessandro Salustri Galal Abushahba Doralisa Morrone Iacopo Fabiani Martin Penicka Asim Katbeh Giuseppe Sammarco Roberta Esposito Ciro Santoro Maria Concetta Pastore Salvatore Comenale Pinto Artem Kalinin Žanna Pičkure Katja Ažman Juvan Anja Zupan Mežnar Augustine Coisne Amandine Coppin Mihaela Maria Opris Dan Octavian Nistor Riitta Paakkanen Tor Biering-Sørensen Flemming Javier Olsen Tomas Lapinskas Jolanta Justina Vaškelyté Laura Galian-Gay Guillem Casas Andreea Iulia Motoc Constantinos Hristou Papadopoulos Savvas Loizos Gergely Ágoston Istvan Szabó Krasimira Hristova Svetlin Netkov Tsonev Elena Galli Dragos Vinereanu Sorina Mihaila Baldea Denisa Muraru Sergio Mondillo Erwan Donal Maurizio Galderisi Bernard Cosyns Thor Edvardsen Bogdan A. Popescu |
| author_sort | Matteo Cameli |
| collection | DOAJ |
| description | Two methods are currently available for left atrial (LA) strain measurement by speckle tracking echocardiography, with two different reference timings for starting the analysis: QRS (QRS-LASr) and P wave (P-LASr). The aim of MASCOT HIT study was to define which of the two was more reproducible, more feasible, and less time consuming. In 26 expert centers, LA strain was analyzed by two different echocardiographers (young vs senior) in a blinded fashion. The study population included: healthy subjects, patients with arterial hypertension or aortic stenosis (LA pressure overload, group 2) and patients with mitral regurgitation or heart failure (LA volume–pressure overload, group 3). Difference between the inter-correlation coefficient (ICC) by the two echocardiographers using the two techniques, feasibility and analysis time of both methods were analyzed. A total of 938 subjects were included: 309 controls, 333 patients in group 2, and 296 patients in group 3. The ICC was comparable between QRS-LASr (0.93) and P-LASr (0.90). The young echocardiographers calculated QRS-LASr in 90% of cases, the expert ones in 95%. The feasibility of P-LASr was 85% by young echocardiographers and 88% by senior ones. QRS-LASr young median time was 110 s (interquartile range, IR, 78-149) vs senior 110 s (IR 78-155); for P-LASr, 120 s (IR 80-165) and 120 s (IR 90-161), respectively. LA strain was feasible in the majority of patients with similar reproducibility for both methods. QRS complex guaranteed a slightly higher feasibility and a lower time wasting compared to the use of P wave as the reference. |
| first_indexed | 2024-03-10T14:52:42Z |
| format | Article |
| id | doaj.art-411192dd36794fb088aae00f004853f2 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T14:52:42Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-411192dd36794fb088aae00f004853f22023-11-20T20:51:08ZengMDPI AGDiagnostics2075-44182020-11-01101194610.3390/diagnostics10110946Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT StudyMatteo Cameli0Marcelo Haertel Miglioranza1Julien Magne2Giulia Elena Mandoli3Giovanni Benfari4Roberta Ancona5Gerolamo Sibilio6Vlatka Reskovic Luksic7Dosen Dejan8Leonardo Griseli9Caroline M. Van De Heyning10Philippe Mortelmans11Blazej Michalski12Karolina Kupczynska13Giovanna Di Giannuario14Fiorella Devito15Raluca Dulgheru16Federica Ilardi17Alessandro Salustri18Galal Abushahba19Doralisa Morrone20Iacopo Fabiani21Martin Penicka22Asim Katbeh23Giuseppe Sammarco24Roberta Esposito25Ciro Santoro26Maria Concetta Pastore27Salvatore Comenale Pinto28Artem Kalinin29Žanna Pičkure30Katja Ažman Juvan31Anja Zupan Mežnar32Augustine Coisne33Amandine Coppin34Mihaela Maria Opris35Dan Octavian Nistor36Riitta Paakkanen37Tor Biering-Sørensen38Flemming Javier Olsen39Tomas Lapinskas40Jolanta Justina Vaškelyté41Laura Galian-Gay42Guillem Casas43Andreea Iulia Motoc44Constantinos Hristou Papadopoulos45Savvas Loizos46Gergely Ágoston47Istvan Szabó48Krasimira Hristova49Svetlin Netkov Tsonev50Elena Galli51Dragos Vinereanu52Sorina Mihaila Baldea53Denisa Muraru54Sergio Mondillo55Erwan Donal56Maurizio Galderisi57Bernard Cosyns58Thor Edvardsen59Bogdan A. Popescu60Department of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, ItalyInstitute of Cardiology, University Foundation of Cardiology, Porto Alegre 90620-000, BrazilCHU Limoges, Hôpital Dupuytren, Service Cardiologie, F-87042, 87042 Limoges, FranceDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, ItalySection of Cardiology, Department of Medicine, University of Verona, 37126 Verona, ItalyUOC Cardiologia/UTIC—“Santa Maria delle Grazie” Hospital Pozzuoli, 80078 Pozzuoli, ItalyUOC Cardiologia/UTIC—“Santa Maria delle Grazie” Hospital Pozzuoli, 80078 Pozzuoli, ItalyDepartment of Cardiovascular Diseases, University Hospital Centre Zagreb, 10000 Zagreb, CroatiaDepartment of Cardiovascular Diseases, University Hospital Centre Zagreb, 10000 Zagreb, CroatiaInstitute of Cardiology, University Foundation of Cardiology, Porto Alegre 90620-000, BrazilDepartment of Cardiology, Antwerp University Hospital, 2650 Edegem, BelgiumDepartment of Cardiology, Antwerp University Hospital, 2650 Edegem, BelgiumDepartment of Cardiology, Medical University of Lodz, 91347 Lodz, PolandDepartment of Cardiology, Medical University of Lodz, 91347 Lodz, PolandUO Cardiologia, Ospedale Infermi di Rimini, 47923 Rimini, ItalyRamazzini Hospital, 41012 Carpi, ItalyCardiology Department—Heart Valve Clinic—University Hospital Liege, B-4000 Liege, BelgiumCardiology Department—Heart Valve Clinic—University Hospital Liege, B-4000 Liege, BelgiumNon-Invasive Department, Heart Hospital—Hamad Medical Corporation, Doha 3050, QatarNon-Invasive Department, Heart Hospital—Hamad Medical Corporation, Doha 3050, QatarCardiothoracic and Vascular Department, Pisa University, 56126 Pisa, ItalyCardiothoracic and Vascular Department, Pisa University, 56126 Pisa, ItalyCardiovascular Research Center Aalst, OLV Clinic, 9300 Aalst, BelgiumCardiovascular Research Center Aalst, OLV Clinic, 9300 Aalst, BelgiumDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padua, 35122 Padua, ItalyDepartment of Advanced Biomedical Sciences, Federico II, University Hospital, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, Federico II, University Hospital, 80131 Naples, ItalyDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, ItalyUOC Cardiologia/UTIC—“Santa Maria delle Grazie” Hospital Pozzuoli, 80078 Pozzuoli, ItalyDepartment “Gailezers”, Riga East Clinical University Hospital, LV-1038 Riga, LatviaDepartment “Gailezers”, Riga East Clinical University Hospital, LV-1038 Riga, LatviaDepartment of Cardiovascular Surgery, University Medical Centre Ljubljana, 1000 Ljubljana, SloveniaCardiology Department, University Medical Centre Ljubljana, 1000 Ljubljana, SloveniaDepartment of Clinical Physiology and Echocardiography—Heart Valve Clinic, Lille University Hospital, 59800 Lille, FranceDepartment of Clinical Physiology and Echocardiography—Heart Valve Clinic, Lille University Hospital, 59800 Lille, FranceInstitute for Emergency Cardiovascular Diseases and Transplant of Targu Mures, 540136 Targu Mures, RomaniaInstitute for Emergency Cardiovascular Diseases and Transplant of Targu Mures, 540136 Targu Mures, RomaniaHeart and Lung Center, Helsinki University Hospital and Helsinki University, 00100 Helsinki, FinlandDepartment of Cardiology, Herlev and Gentofte Hospital, University of Copenhagen, 2900 Copenhagen, DenmarkDepartment of Cardiology, Herlev and Gentofte Hospital, University of Copenhagen, 2900 Copenhagen, DenmarkDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, 44307 Kaunas, LithuaniaDepartment of Cardiology, Medical Academy, Lithuanian University of Health Sciences, 44307 Kaunas, LithuaniaDepartment of Cardiology, Hospital Universitari Vall d’Hebron, 08035 Barcelona, SpainDepartment of Cardiology, Hospital Universitari Vall d’Hebron, 08035 Barcelona, SpainCentre for Cardiovascular Diseases, University Hospital of Brussels, B-1090 Brussels, BelgiumKorgialenio Benakio—Red Cross Hospital, 115 26 Athens, GreeceKorgialenio Benakio—Red Cross Hospital, 115 26 Athens, GreeceDepartment of Family Medicine, University of Szeged, H-6725 Szeged, HungaryDepartment of Family Medicine, University of Szeged, H-6725 Szeged, HungaryDepartment of Noninvasive Functional Diagnostic and Imaging, National Heart Hospital, 1309 Sofia, BulgariaDepartment of Noninvasive Functional Diagnostic and Imaging, National Heart Hospital, 1309 Sofia, BulgariaCentre Hospitalier Universitaire de Rennes, Inserm, University of Rennes, LTSI—UMR 1099, F-35000 Rennes, FranceDepartment of Cardiology, University of Medicine and Pharmacy Carol Davila—Emergency and University Hospital, 050474 Bucharest, RomaniaDepartment of Cardiology, University of Medicine and Pharmacy Carol Davila—Emergency and University Hospital, 050474 Bucharest, RomaniaDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padua, 35122 Padua, ItalyDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, ItalyCentre Hospitalier Universitaire de Rennes, Inserm, University of Rennes, LTSI—UMR 1099, F-35000 Rennes, FranceDepartment of Advanced Biomedical Sciences, Federico II, University Hospital, 80131 Naples, ItalyCentre for Cardiovascular Diseases, University Hospital of Brussels, B-1090 Brussels, BelgiumCenter for Cardiological Innovation, Department of Cardiology, Oslo University Hospital, Rikshospitalet, 0372 Oslo, NorwayDepartment of Cardiology, University of Medicine and Pharmacy “Carol Davila”—Euroecolab, Emergency Institute for Cardiovascular Diseases “Prof. Dr. C. C. Iliescu”, Sos. Fundeni 258, 022328 Bucharest, RomaniaTwo methods are currently available for left atrial (LA) strain measurement by speckle tracking echocardiography, with two different reference timings for starting the analysis: QRS (QRS-LASr) and P wave (P-LASr). The aim of MASCOT HIT study was to define which of the two was more reproducible, more feasible, and less time consuming. In 26 expert centers, LA strain was analyzed by two different echocardiographers (young vs senior) in a blinded fashion. The study population included: healthy subjects, patients with arterial hypertension or aortic stenosis (LA pressure overload, group 2) and patients with mitral regurgitation or heart failure (LA volume–pressure overload, group 3). Difference between the inter-correlation coefficient (ICC) by the two echocardiographers using the two techniques, feasibility and analysis time of both methods were analyzed. A total of 938 subjects were included: 309 controls, 333 patients in group 2, and 296 patients in group 3. The ICC was comparable between QRS-LASr (0.93) and P-LASr (0.90). The young echocardiographers calculated QRS-LASr in 90% of cases, the expert ones in 95%. The feasibility of P-LASr was 85% by young echocardiographers and 88% by senior ones. QRS-LASr young median time was 110 s (interquartile range, IR, 78-149) vs senior 110 s (IR 78-155); for P-LASr, 120 s (IR 80-165) and 120 s (IR 90-161), respectively. LA strain was feasible in the majority of patients with similar reproducibility for both methods. QRS complex guaranteed a slightly higher feasibility and a lower time wasting compared to the use of P wave as the reference.https://www.mdpi.com/2075-4418/10/11/946speckle tracking echocardiographyleft atrial strainreference pointmulti-centric studystandardization |
| spellingShingle | Matteo Cameli Marcelo Haertel Miglioranza Julien Magne Giulia Elena Mandoli Giovanni Benfari Roberta Ancona Gerolamo Sibilio Vlatka Reskovic Luksic Dosen Dejan Leonardo Griseli Caroline M. Van De Heyning Philippe Mortelmans Blazej Michalski Karolina Kupczynska Giovanna Di Giannuario Fiorella Devito Raluca Dulgheru Federica Ilardi Alessandro Salustri Galal Abushahba Doralisa Morrone Iacopo Fabiani Martin Penicka Asim Katbeh Giuseppe Sammarco Roberta Esposito Ciro Santoro Maria Concetta Pastore Salvatore Comenale Pinto Artem Kalinin Žanna Pičkure Katja Ažman Juvan Anja Zupan Mežnar Augustine Coisne Amandine Coppin Mihaela Maria Opris Dan Octavian Nistor Riitta Paakkanen Tor Biering-Sørensen Flemming Javier Olsen Tomas Lapinskas Jolanta Justina Vaškelyté Laura Galian-Gay Guillem Casas Andreea Iulia Motoc Constantinos Hristou Papadopoulos Savvas Loizos Gergely Ágoston Istvan Szabó Krasimira Hristova Svetlin Netkov Tsonev Elena Galli Dragos Vinereanu Sorina Mihaila Baldea Denisa Muraru Sergio Mondillo Erwan Donal Maurizio Galderisi Bernard Cosyns Thor Edvardsen Bogdan A. Popescu Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study Diagnostics speckle tracking echocardiography left atrial strain reference point multi-centric study standardization |
| title | Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study |
| title_full | Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study |
| title_fullStr | Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study |
| title_full_unstemmed | Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study |
| title_short | Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study |
| title_sort | multicentric atrial strain comparison between two different modalities mascot hit study |
| topic | speckle tracking echocardiography left atrial strain reference point multi-centric study standardization |
| url | https://www.mdpi.com/2075-4418/10/11/946 |
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