Characterization of somatic structural variations in 528 Chinese individuals with Esophageal squamous cell carcinoma

Characterization of somatic structural variations in 528 Chinese individuals with Esophageal squamous cell carcinoma

The biological and clinical implications of high genome instability in esophageal squamous cell carcinoma (ESCC) remain to be explored. Here, the authors analyse 528 whole genomes and investigate the landscape and molecular mechanisms underlying structural variations in ESCC patients.

Bibliographic Details
Main Authors: Heyang Cui, Yong Zhou, Fang Wang, Caixia Cheng, Weimin Zhang, Ruifang Sun, Ling Zhang, Yanghui Bi, Min Guo, Yan Zhou, Xinhui Wang, Jiaxin Ren, Ruibing Bai, Ning Ding, Chen Cheng, Longlong Wang, Xuehan Zhuang, Mingwei Gao, Yongjia Weng, Yueguang Wu, Huijuan Liu, Shuaicheng Li, Shubin Wang, Xiaolong Cheng, Yongping Cui, Zhihua Liu, Qimin Zhan
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33994-3

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