SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTS
ABSTRACT Objective: To present two clinical cases of pediatric Cushing disease caused by adrenocorticotropic hormone secreting pituitary adenomas, which were diagnosed by magnetic resonance imaging using 3 Tesla technology. Case description: Two cases of Cushing disease in 9-year-old children ar...
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| Format: | Article |
| Language: | English |
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Sociedade de Pediatria de São Paulo
2019-05-01
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| Series: | Revista Paulista de Pediatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822019005008105&lng=en&tlng=en |
| _version_ | 1819049765190500352 |
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| author | Leila Warszawski Gabriel Santi Calabria Esteves Ariane Pagnocelli Bruna de Lacerda Bouzon Sayra Lacerda de Oliveira |
| author_facet | Leila Warszawski Gabriel Santi Calabria Esteves Ariane Pagnocelli Bruna de Lacerda Bouzon Sayra Lacerda de Oliveira |
| author_sort | Leila Warszawski |
| collection | DOAJ |
| description | ABSTRACT Objective: To present two clinical cases of pediatric Cushing disease caused by adrenocorticotropic hormone secreting pituitary adenomas, which were diagnosed by magnetic resonance imaging using 3 Tesla technology. Case description: Two cases of Cushing disease in 9-year-old children are reported. Both children presented pituitary adenomas that were smaller than 5 mm at their largest diameter, and which were not seen by standard 1.5 Tesla resonance. One of the patients was submitted to bilateral and simultaneous catheterization of the inferior petrosal sinus, but the result was undetermined. In both cases, the pituitary adenoma was detected by 3 Tesla magnetic resonance imaging. Both patients underwent transsphenoidal surgery and were cured. Comments: Cushing disease presents high morbidity. Therefore, early diagnosis and prompt treatment are essential. It is usually caused by adenomas that are smaller than 5 mm in diameter. Surgery is the first line of treatment, and effective methods of locating the adenoma are necessary for greater therapeutic success. This report suggests that the 3 Tesla magnetic resonance imaging is more sensitive, and thus able to detect pituitary microadenomas (largest diameter <10 mm). This exam may be indicated as a low-morbidity diagnostic tool for finding pituitary microadenomas in Cushing disease that are not visualized by 1.5 Tesla magnetic resonance imaging. |
| first_indexed | 2024-12-21T11:37:21Z |
| format | Article |
| id | doaj.art-411474bca325439eba6e42c963dc7991 |
| institution | Directory Open Access Journal |
| issn | 1984-0462 |
| language | English |
| last_indexed | 2024-12-21T11:37:21Z |
| publishDate | 2019-05-01 |
| publisher | Sociedade de Pediatria de São Paulo |
| record_format | Article |
| series | Revista Paulista de Pediatria |
| spelling | doaj.art-411474bca325439eba6e42c963dc79912022-12-21T19:05:24ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622019-05-01010.1590/1984-0462/;2019;37;3;00009S0103-05822019005008105SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTSLeila WarszawskiGabriel Santi Calabria EstevesAriane PagnocelliBruna de Lacerda BouzonSayra Lacerda de OliveiraABSTRACT Objective: To present two clinical cases of pediatric Cushing disease caused by adrenocorticotropic hormone secreting pituitary adenomas, which were diagnosed by magnetic resonance imaging using 3 Tesla technology. Case description: Two cases of Cushing disease in 9-year-old children are reported. Both children presented pituitary adenomas that were smaller than 5 mm at their largest diameter, and which were not seen by standard 1.5 Tesla resonance. One of the patients was submitted to bilateral and simultaneous catheterization of the inferior petrosal sinus, but the result was undetermined. In both cases, the pituitary adenoma was detected by 3 Tesla magnetic resonance imaging. Both patients underwent transsphenoidal surgery and were cured. Comments: Cushing disease presents high morbidity. Therefore, early diagnosis and prompt treatment are essential. It is usually caused by adenomas that are smaller than 5 mm in diameter. Surgery is the first line of treatment, and effective methods of locating the adenoma are necessary for greater therapeutic success. This report suggests that the 3 Tesla magnetic resonance imaging is more sensitive, and thus able to detect pituitary microadenomas (largest diameter <10 mm). This exam may be indicated as a low-morbidity diagnostic tool for finding pituitary microadenomas in Cushing disease that are not visualized by 1.5 Tesla magnetic resonance imaging.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822019005008105&lng=en&tlng=enHipófiseAdenomaSíndrome de CushingCriançaRessonância magnética |
| spellingShingle | Leila Warszawski Gabriel Santi Calabria Esteves Ariane Pagnocelli Bruna de Lacerda Bouzon Sayra Lacerda de Oliveira SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTS Revista Paulista de Pediatria Hipófise Adenoma Síndrome de Cushing Criança Ressonância magnética |
| title | SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTS |
| title_full | SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTS |
| title_fullStr | SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTS |
| title_full_unstemmed | SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTS |
| title_short | SELLA TURCICA 3T MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CUSHING’S DISEASE IN CHILDREN: TWO CASE REPORTS |
| title_sort | sella turcica 3t magnetic resonance imaging in the diagnosis of cushing s disease in children two case reports |
| topic | Hipófise Adenoma Síndrome de Cushing Criança Ressonância magnética |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822019005008105&lng=en&tlng=en |
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