Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche
Abstract The adult mammalian brain retains some capacity to replenish neurons and glia, holding promise for brain regeneration. Thus, understanding the mechanisms controlling adult neural stem cell (NSC) differentiation is crucial. Paradoxically, adult NSCs in the subependymal zone transcribe genes...
Main Authors: | Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-47092-z |
Similar Items
-
ENVIRONMENTAL ENRICHMENT SHAPES MICROGLIA IN THE ADULT HIPPOCAMPAL NEUROGENIC NICHE
by: Noelia Rodriguez-Iglesias, et al.
Published: (2023-10-01) -
Homemade: building the structure of the neurogenic niche
by: Ghanim Fajish Valamparamban, et al.
Published: (2023-12-01) -
Exosomes as novel regulators of adult neurogenic niches
by: Luis Federico Batiz, et al.
Published: (2016-01-01) -
Development of the adult neurogenic niche in the hippocampus of mice
by: Zeina eNicola, et al.
Published: (2015-05-01) -
Mapping of potential neurogenic niche in the human temporal lobe
by: Adriano Barreto Nogueira
Published: (2014-10-01)