Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche

Abstract The adult mammalian brain retains some capacity to replenish neurons and glia, holding promise for brain regeneration. Thus, understanding the mechanisms controlling adult neural stem cell (NSC) differentiation is crucial. Paradoxically, adult NSCs in the subependymal zone transcribe genes...

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Bibliographic Details
Main Authors: Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47092-z

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