Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia
Abstract The aim of this paper is to propose a new non-invasive methodology to estimate thermogenesis in newborns with perinatal asphyxia (PA) undergoing therapeutic hypothermia (TH). Metabolic heat production (with respect to either a neonate’s body mass or its body surface) is calculated from the...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2020-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-020-79009-3 |
| _version_ | 1818751877736562688 |
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| author | Wojciech Walas Dominika Bandoła Ziemowit Ostrowski Marek Rojczyk Anna Mączko Zenon Halaba Andrzej J. Nowak |
| author_facet | Wojciech Walas Dominika Bandoła Ziemowit Ostrowski Marek Rojczyk Anna Mączko Zenon Halaba Andrzej J. Nowak |
| author_sort | Wojciech Walas |
| collection | DOAJ |
| description | Abstract The aim of this paper is to propose a new non-invasive methodology to estimate thermogenesis in newborns with perinatal asphyxia (PA) undergoing therapeutic hypothermia (TH). Metabolic heat production (with respect to either a neonate’s body mass or its body surface) is calculated from the newborn’s heat balance, estimating all remaining terms of this heat balance utilising results of only non-invasive thermal measurements. The measurement devices work with standard equipment used for therapeutic hypothermia and are equipped with the Global System for Mobile Communications (GSM), which allows one to record and monitor the course of the therapy remotely (using an internet browser) without disturbing the medical personnel. This methodology allows one to estimate thermogenesis in newborns with perinatal asphyxia undergoing therapeutic hypothermia. It also offers information about instantaneous values of the rate of cooling together with values of remaining rates of heat transfer. It also shows the trend of any changes, which are recorded during treatment. Having information about all components of the heat balance one is able to facilitate comparison of results obtained for different patients, in whom these components may differ. The proposed method can be a new tool for measuring heat balance with the possibility of offering better predictions regarding short-term neurologic outcomes and tailored management in newborns treated by TH. |
| first_indexed | 2024-12-18T04:42:33Z |
| format | Article |
| id | doaj.art-411f3bbd1a1e4c37accd20f86cf5aa0e |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-18T04:42:33Z |
| publishDate | 2020-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-411f3bbd1a1e4c37accd20f86cf5aa0e2022-12-21T21:20:40ZengNature PortfolioScientific Reports2045-23222020-12-0110111110.1038/s41598-020-79009-3Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermiaWojciech Walas0Dominika Bandoła1Ziemowit Ostrowski2Marek Rojczyk3Anna Mączko4Zenon Halaba5Andrzej J. Nowak6Paediatric and Neonatal Intensive Care Unit, University Clinical HospitalDepartment of Thermal Technology, Silesian University of TechnologyDepartment of Thermal Technology, Silesian University of TechnologyDepartment of Thermal Technology, Silesian University of TechnologyPaediatric and Neonatal Intensive Care Unit, University Clinical HospitalDepartment of Paediatrics, Institute of Medical Sciences, University of OpoleDepartment of Thermal Technology, Silesian University of TechnologyAbstract The aim of this paper is to propose a new non-invasive methodology to estimate thermogenesis in newborns with perinatal asphyxia (PA) undergoing therapeutic hypothermia (TH). Metabolic heat production (with respect to either a neonate’s body mass or its body surface) is calculated from the newborn’s heat balance, estimating all remaining terms of this heat balance utilising results of only non-invasive thermal measurements. The measurement devices work with standard equipment used for therapeutic hypothermia and are equipped with the Global System for Mobile Communications (GSM), which allows one to record and monitor the course of the therapy remotely (using an internet browser) without disturbing the medical personnel. This methodology allows one to estimate thermogenesis in newborns with perinatal asphyxia undergoing therapeutic hypothermia. It also offers information about instantaneous values of the rate of cooling together with values of remaining rates of heat transfer. It also shows the trend of any changes, which are recorded during treatment. Having information about all components of the heat balance one is able to facilitate comparison of results obtained for different patients, in whom these components may differ. The proposed method can be a new tool for measuring heat balance with the possibility of offering better predictions regarding short-term neurologic outcomes and tailored management in newborns treated by TH.https://doi.org/10.1038/s41598-020-79009-3 |
| spellingShingle | Wojciech Walas Dominika Bandoła Ziemowit Ostrowski Marek Rojczyk Anna Mączko Zenon Halaba Andrzej J. Nowak Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia Scientific Reports |
| title | Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia |
| title_full | Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia |
| title_fullStr | Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia |
| title_full_unstemmed | Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia |
| title_short | Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia |
| title_sort | theoretical basis for the use of non invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia |
| url | https://doi.org/10.1038/s41598-020-79009-3 |
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