Metabolic engineering Saccharomyces cerevisiae for de novo production of the sesquiterpenoid (+)-nootkatone

Metabolic engineering Saccharomyces cerevisiae for de novo production of the sesquiterpenoid (+)-nootkatone

Abstract Background (+)-Nootkatone is a highly valued sesquiterpenoid compound, exhibiting a typical grapefruit aroma and various desired biological activities for use as aromatics and pharmaceuticals. The high commercial demand of (+)-nootkatone is predominately met by chemical synthesis, which ent...

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Bibliographic Details
Main Authors: Xiangfeng Meng, Hui Liu, Wenqiang Xu, Weixin Zhang, Zheng Wang, Weifeng Liu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Microbial Cell Factories
Subjects:
(+)-Valencene
(+)-Nootkatone
Saccharomyces cerevisiae
Sesquiterpene
Dehydrogenases
Online Access:https://doi.org/10.1186/s12934-020-1295-6

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