Epidemiology and treatment utilization for Canadian patients with migraine: a literature review

The objective of this narrative review was to identify real-world evidence regarding the burden of migraine in Canada. We conducted a literature search in MEDLINE, Embase, and the Cochrane Database of Systematic Reviews for studies published between August 2010 and August 2020. Of the 3269 publicati...

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Main Authors: Erin B Graves, Brittany R Gerber, Patrick S Berrigan, Eileen Shaw, Tara M Cowling, Marie-Pier Ladouceur, Joanna K Bougie
Format: Article
Language:English
Published: SAGE Publishing 2022-09-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605221126380
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author Erin B Graves
Brittany R Gerber
Patrick S Berrigan
Eileen Shaw
Tara M Cowling
Marie-Pier Ladouceur
Joanna K Bougie
author_facet Erin B Graves
Brittany R Gerber
Patrick S Berrigan
Eileen Shaw
Tara M Cowling
Marie-Pier Ladouceur
Joanna K Bougie
author_sort Erin B Graves
collection DOAJ
description The objective of this narrative review was to identify real-world evidence regarding the burden of migraine in Canada. We conducted a literature search in MEDLINE, Embase, and the Cochrane Database of Systematic Reviews for studies published between August 2010 and August 2020. Of the 3269 publications identified, 29 studies were included. Prevalence estimates varied widely across Canada, and mental health comorbidities were common. Individuals with migraine have a lower quality of life, detrimental impact on workforce productivity, and higher rates of health care resource utilization (HCRU), with HCRU and costs highest among those with chronic migraine. We found inconsistencies in care, including underutilization of medications such as triptans, and varied utilization of over-the-counter and prescription medications. Increased medication use was identified among those with chronic migraine, and only a small number of patients used migraine preventive medications. The burden of migraine in Canada is substantial. Reduced quality of life and workforce productivity, increased HCRU and costs, and underutilization of triptans and migraine preventive medications highlight an important need for more effective management of individuals with migraine.
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spelling doaj.art-4123a4e9983f45ca893cc0a51f8044cc2022-12-22T03:48:50ZengSAGE PublishingJournal of International Medical Research1473-23002022-09-015010.1177/03000605221126380Epidemiology and treatment utilization for Canadian patients with migraine: a literature reviewErin B GravesBrittany R GerberPatrick S BerriganEileen ShawTara M CowlingMarie-Pier LadouceurJoanna K BougieThe objective of this narrative review was to identify real-world evidence regarding the burden of migraine in Canada. We conducted a literature search in MEDLINE, Embase, and the Cochrane Database of Systematic Reviews for studies published between August 2010 and August 2020. Of the 3269 publications identified, 29 studies were included. Prevalence estimates varied widely across Canada, and mental health comorbidities were common. Individuals with migraine have a lower quality of life, detrimental impact on workforce productivity, and higher rates of health care resource utilization (HCRU), with HCRU and costs highest among those with chronic migraine. We found inconsistencies in care, including underutilization of medications such as triptans, and varied utilization of over-the-counter and prescription medications. Increased medication use was identified among those with chronic migraine, and only a small number of patients used migraine preventive medications. The burden of migraine in Canada is substantial. Reduced quality of life and workforce productivity, increased HCRU and costs, and underutilization of triptans and migraine preventive medications highlight an important need for more effective management of individuals with migraine.https://doi.org/10.1177/03000605221126380
spellingShingle Erin B Graves
Brittany R Gerber
Patrick S Berrigan
Eileen Shaw
Tara M Cowling
Marie-Pier Ladouceur
Joanna K Bougie
Epidemiology and treatment utilization for Canadian patients with migraine: a literature review
Journal of International Medical Research
title Epidemiology and treatment utilization for Canadian patients with migraine: a literature review
title_full Epidemiology and treatment utilization for Canadian patients with migraine: a literature review
title_fullStr Epidemiology and treatment utilization for Canadian patients with migraine: a literature review
title_full_unstemmed Epidemiology and treatment utilization for Canadian patients with migraine: a literature review
title_short Epidemiology and treatment utilization for Canadian patients with migraine: a literature review
title_sort epidemiology and treatment utilization for canadian patients with migraine a literature review
url https://doi.org/10.1177/03000605221126380
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