Nrf2 regulates glucose uptake and metabolism in neurons and astrocytes

Nrf2 regulates glucose uptake and metabolism in neurons and astrocytes

The transcription factor Nrf2 and its repressor Keap1 mediate cell stress adaptation by inducing expression of genes regulating cellular detoxification, antioxidant defence and energy metabolism. Energy production and antioxidant defence employ NADH and NADPH respectively as essential metabolic cofa...

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Bibliographic Details
Main Authors:	Noemí Esteras, Thomas S. Blacker, Evgeny A. Zherebtsov, Olga A. Stelmashuk, Ying Zhang, W. Christian Wigley, Michael R. Duchen, Albena T. Dinkova-Kostova, Andrey Y. Abramov
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Series:	Redox Biology
Subjects:	Nrf2 Glucose metabolism Mitochondria NADH NADPH Brain
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231723000733

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