Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

Abstract Background The MALAT1 lncRNA acts as an oncogene in Prostate cancer (PC); thus, it can be severe as a cancer biomarker. Methods Using bioinformatics datasets including (HTSeq-Counts, GDC, and TCGA) 5501 gene expression profiling specimens were gathered. Then, expression profiles and sample...

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Bibliographic Details
Main Authors: Soraya Ahmadi-Balootaki, Abbas Doosti, Mojtaba Jafarinia, Hamed Reza Goodarzi
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Genes and Environment
Subjects:
Online Access:https://doi.org/10.1186/s41021-022-00252-3