Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment
<p>Abstract</p> <p>Background</p> <p>To describe the clinical presentation of suprasellar cysts (SSCs) and surgical indications, and compare the treatment methods of endoscopic ventriculocystostomy (VC) and ventriculocystocisternotomy (VCC).</p> <p>Methods&l...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2011-05-01
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| Series: | BMC Neurology |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1471-2377/11/52 |
| _version_ | 1818270033840701440 |
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| author | Zhang Ya-Zhuo Zong Xu-Yi Wang Xin-Sheng Gui Song-Bai Li Chu-Zhong |
| author_facet | Zhang Ya-Zhuo Zong Xu-Yi Wang Xin-Sheng Gui Song-Bai Li Chu-Zhong |
| author_sort | Zhang Ya-Zhuo |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>To describe the clinical presentation of suprasellar cysts (SSCs) and surgical indications, and compare the treatment methods of endoscopic ventriculocystostomy (VC) and ventriculocystocisternotomy (VCC).</p> <p>Methods</p> <p>We retrospectively reviewed the records of 73 consecutive patients with SSC who were treated between June 2002 and September 2009. Twenty-two patients were treated with VC and 51 with VCC. Outcome was assessed by clinical examination and magnetic resonance imaging.</p> <p>Results</p> <p>The patients were divided into five groups based on age at presentation: age less than 1 year (n = 6), 1-5 years (n = 36), 6-10 years (n = 15), 11-20 years (n = 11), and 21-53 years (n = 5). The main clinical presentations were macrocrania (100%), motor deficits (50%), and gaze disturbance (33.3%) in the age less than 1 year group; macrocrania (75%), motor deficits (63.9%), and gaze disturbance (27.8%) in the 1-5 years group; macrocrania (46.7%), symptoms of raised intracranial pressure (ICP) (40.0%), endocrine dysfunction (40%), and seizures (33.3%) in the 6-10 years group; symptoms of raised ICP (54.5%), endocrine dysfunction (54.5%), and reduced visual field or acuity (36.4%) in the 11-20 years group; and symptoms of raised ICP (80.0%) and reduced visual field or acuity (40.0%) in the 21-53 years group. The overall success rate of endoscopic fenestration was 90.4%. A Kaplan-Meier curve for long-term efficacy of the two treatment modalities showed better results for VCC than for VC (p = 0.008).</p> <p>Conclusions</p> <p>Different age groups with SSCs have different main clinical presentations. VCC appears to be more efficacious than VC.</p> |
| first_indexed | 2024-12-12T21:03:51Z |
| format | Article |
| id | doaj.art-412686a793534bf6a8adefba4de97dd9 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-12-12T21:03:51Z |
| publishDate | 2011-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-412686a793534bf6a8adefba4de97dd92022-12-22T00:12:04ZengBMCBMC Neurology1471-23772011-05-011115210.1186/1471-2377-11-52Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatmentZhang Ya-ZhuoZong Xu-YiWang Xin-ShengGui Song-BaiLi Chu-Zhong<p>Abstract</p> <p>Background</p> <p>To describe the clinical presentation of suprasellar cysts (SSCs) and surgical indications, and compare the treatment methods of endoscopic ventriculocystostomy (VC) and ventriculocystocisternotomy (VCC).</p> <p>Methods</p> <p>We retrospectively reviewed the records of 73 consecutive patients with SSC who were treated between June 2002 and September 2009. Twenty-two patients were treated with VC and 51 with VCC. Outcome was assessed by clinical examination and magnetic resonance imaging.</p> <p>Results</p> <p>The patients were divided into five groups based on age at presentation: age less than 1 year (n = 6), 1-5 years (n = 36), 6-10 years (n = 15), 11-20 years (n = 11), and 21-53 years (n = 5). The main clinical presentations were macrocrania (100%), motor deficits (50%), and gaze disturbance (33.3%) in the age less than 1 year group; macrocrania (75%), motor deficits (63.9%), and gaze disturbance (27.8%) in the 1-5 years group; macrocrania (46.7%), symptoms of raised intracranial pressure (ICP) (40.0%), endocrine dysfunction (40%), and seizures (33.3%) in the 6-10 years group; symptoms of raised ICP (54.5%), endocrine dysfunction (54.5%), and reduced visual field or acuity (36.4%) in the 11-20 years group; and symptoms of raised ICP (80.0%) and reduced visual field or acuity (40.0%) in the 21-53 years group. The overall success rate of endoscopic fenestration was 90.4%. A Kaplan-Meier curve for long-term efficacy of the two treatment modalities showed better results for VCC than for VC (p = 0.008).</p> <p>Conclusions</p> <p>Different age groups with SSCs have different main clinical presentations. VCC appears to be more efficacious than VC.</p>http://www.biomedcentral.com/1471-2377/11/52Suprasellar cystclinical presentationendoscopic fenestrationoutcome |
| spellingShingle | Zhang Ya-Zhuo Zong Xu-Yi Wang Xin-Sheng Gui Song-Bai Li Chu-Zhong Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment BMC Neurology Suprasellar cyst clinical presentation endoscopic fenestration outcome |
| title | Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment |
| title_full | Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment |
| title_fullStr | Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment |
| title_full_unstemmed | Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment |
| title_short | Suprasellar cysts: clinical presentation, surgical indications, and optimal surgical treatment |
| title_sort | suprasellar cysts clinical presentation surgical indications and optimal surgical treatment |
| topic | Suprasellar cyst clinical presentation endoscopic fenestration outcome |
| url | http://www.biomedcentral.com/1471-2377/11/52 |
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