Tubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.

Tubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.

The cytoplasmic loop between the second and third transmembrane segments is pivotal in the regulation of TRESK (TWIK-related spinal cord K+ channel, K2P18.1, KCNK18). Calcineurin binds to this region and activates the channel by dephosphorylation in response to the calcium signal. Phosphorylation-de...

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Bibliographic Details
Main Authors: Péter Enyedi, Irén Veres, Gabriella Braun, Gábor Czirják
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4022642?pdf=render

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