Hemorrhagic Aspects of Gaucher Disease

Hemorrhagic Aspects of Gaucher Disease

Gaucher disease (GD) is an inherited lysosomal disorder, originating from deficient activity of the lysosomal enzyme glucocerebrosidase (GCase). Normally, GCase hydrolyzes glucocerebroside (GC) to glucose and ceramide; however, impaired activity of this enzyme leads to the accumulation of GC in macr...

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Bibliographic Details
Main Author: Hanna Rsenbaum
Format: Article
Language:English
Published: Rambam Health Care Campus 2014-10-01
Series:Rambam Maimonides Medical Journal
Subjects:
Enzyme replacement therapy
Gaucher disease
glucocerebroside
hemostatic abnormalities
Online Access:http://rmmj.org.il/Pages/ArticleHTM.aspx?manuId=451

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