The comparison of estrogen metabolites between active and inactive postmenopausal women
Introduction: Regular physical activity may alter estrogen metabolism. The aim of the present study was to compare estrogen metabolites between active and inactive postmenopausal women. Materials and Methods: 75 postmenopausal women were asked to fill in the Beck questionnaire. Based on the question...
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| Format: | Article |
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Jahrom University of Medical Sciences
2013-06-01
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| Series: | فصلنامه دانشگاه علوم پزشکی جهرم |
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| Online Access: | http://jmj.jums.ac.ir/article-1-190-en.html |
| _version_ | 1818576176574103552 |
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| author | Amirhossein Haghighi Rouya Askari Mahdi Hedayati Asmae Damanpak |
| author_facet | Amirhossein Haghighi Rouya Askari Mahdi Hedayati Asmae Damanpak |
| author_sort | Amirhossein Haghighi |
| collection | DOAJ |
| description | Introduction: Regular physical activity may alter estrogen metabolism. The aim of the present study was to compare estrogen metabolites between active and inactive postmenopausal women. Materials and Methods: 75 postmenopausal women were asked to fill in the Beck questionnaire. Based on the questionnaire scales, they were divided into two groups: active and inactive. Blood samples were taken in fasting state from all subjects and serum concentration of 2-hydroxyestron and 16-hydroxyestron metabolites and their ratios measured. Independent t-test was used for data analysis. Results: The results showed that 2-hydroxyestron metabolite level and 2-hydroxyestron/16-hydroxyestron ratio were significantly higher among active postmenopausal women than inactive postmenopausal women but 16-hydroxyestron metabolite level was significantly lower among active postmenopausal women than inactive postmenopausal women. Conclusion: It is concluded that long-term physical activity can reduce breast cancer risk in postmenopausal women through influencing the estrogen metabolites. |
| first_indexed | 2024-12-16T06:09:52Z |
| format | Article |
| id | doaj.art-412ece8225534adab226f526cd214d36 |
| institution | Directory Open Access Journal |
| issn | 2008-7993 2008-8442 |
| language | fas |
| last_indexed | 2024-12-16T06:09:52Z |
| publishDate | 2013-06-01 |
| publisher | Jahrom University of Medical Sciences |
| record_format | Article |
| series | فصلنامه دانشگاه علوم پزشکی جهرم |
| spelling | doaj.art-412ece8225534adab226f526cd214d362022-12-21T22:41:25ZfasJahrom University of Medical Sciencesفصلنامه دانشگاه علوم پزشکی جهرم2008-79932008-84422013-06-011122935The comparison of estrogen metabolites between active and inactive postmenopausal womenAmirhossein Haghighi0Rouya Askari1Mahdi Hedayati2Asmae Damanpak3 Introduction: Regular physical activity may alter estrogen metabolism. The aim of the present study was to compare estrogen metabolites between active and inactive postmenopausal women. Materials and Methods: 75 postmenopausal women were asked to fill in the Beck questionnaire. Based on the questionnaire scales, they were divided into two groups: active and inactive. Blood samples were taken in fasting state from all subjects and serum concentration of 2-hydroxyestron and 16-hydroxyestron metabolites and their ratios measured. Independent t-test was used for data analysis. Results: The results showed that 2-hydroxyestron metabolite level and 2-hydroxyestron/16-hydroxyestron ratio were significantly higher among active postmenopausal women than inactive postmenopausal women but 16-hydroxyestron metabolite level was significantly lower among active postmenopausal women than inactive postmenopausal women. Conclusion: It is concluded that long-term physical activity can reduce breast cancer risk in postmenopausal women through influencing the estrogen metabolites.http://jmj.jums.ac.ir/article-1-190-en.htmlphysical activitymetabolitesestrogenpostmenopausalcancer |
| spellingShingle | Amirhossein Haghighi Rouya Askari Mahdi Hedayati Asmae Damanpak The comparison of estrogen metabolites between active and inactive postmenopausal women فصلنامه دانشگاه علوم پزشکی جهرم physical activity metabolites estrogen postmenopausal cancer |
| title | The comparison of estrogen metabolites between active and inactive postmenopausal women |
| title_full | The comparison of estrogen metabolites between active and inactive postmenopausal women |
| title_fullStr | The comparison of estrogen metabolites between active and inactive postmenopausal women |
| title_full_unstemmed | The comparison of estrogen metabolites between active and inactive postmenopausal women |
| title_short | The comparison of estrogen metabolites between active and inactive postmenopausal women |
| title_sort | comparison of estrogen metabolites between active and inactive postmenopausal women |
| topic | physical activity metabolites estrogen postmenopausal cancer |
| url | http://jmj.jums.ac.ir/article-1-190-en.html |
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