The Influenza Virus Protein PB1-F2 Increases Viral Pathogenesis through Neutrophil Recruitment and NK Cells Inhibition.
The influenza A virus (IAV) PB1-F2 protein is a virulence factor contributing to the pathogenesis observed during IAV infections in mammals. In this study, using a mouse model, we compared the host response associated with PB1-F2 with an early transcriptomic signature that was previously associated...
Main Authors: | Aurore Vidy, Pauline Maisonnasse, Bruno Da Costa, Bernard Delmas, Christophe Chevalier, Ronan Le Goffic |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5087861?pdf=render |
Similar Items
-
Impact of the influenza protein PB1-F2 on the biochemical composition of human epithelial cells revealed by synchrotron Fourier transform infrared spectromicroscopy
by: Olivier Leymarie, et al.
Published: (2019-10-01) -
PB1-F2 attenuates virulence of highly pathogenic avian H5N1 influenza virus in chickens.
by: Olivier Leymarie, et al.
Published: (2014-01-01) -
Kinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infection.
by: Olivier Leymarie, et al.
Published: (2013-01-01) -
Comparison of PB1-F2 Proximity Interactomes Reveals Functional Differences between a Human and an Avian Influenza Virus
by: Joëlle Mettier, et al.
Published: (2023-01-01) -
Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
by: Ronan Le Goffic, et al.
Published: (2011-08-01)