The diversity of trophoblast cells and niches of placenta accreta spectrum disorders revealed by single-cell RNA sequencing

The diversity of trophoblast cells and niches of placenta accreta spectrum disorders revealed by single-cell RNA sequencing

Placenta accreta spectrum disorders (PAS) are severe pregnancy complications that occur when extravillous trophoblast cells (EVTs) invade beyond the uterine inner myometrium and are characterized by hypervascularity on prenatal ultrasound and catastrophic postpartum hemorrhage. The potential mechani...

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Bibliographic Details
Main Authors: Jingmei Ma, Yawei Liu, Zhirong Guo, Run Sun, Xinrui Yang, Weiran Zheng, Yongdan Ma, Yin Rong, Hongmei Wang, Huixia Yang, Zhenyu Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
placenta
trophoblast
single-cell sequencing
pathogenesis
placenta accreta spectrum
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1044198/full

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