Potential Therapeutic Effects of the Neural Stem Cell-Targeting Antibody Nilo1 in Patient-Derived Glioblastoma Stem Cells

Potential Therapeutic Effects of the Neural Stem Cell-Targeting Antibody Nilo1 in Patient-Derived Glioblastoma Stem Cells

Glioblastoma (GBM) is the most devastating and least treatable brain tumor with median survival <15 months and extremely high recurrence rates. Promising results of immune checkpoint blockade obtained from pre-clinical studies in mice did not translate to clinic, and new strategies are urgent...

Full description

Bibliographic Details
Main Authors: Gorjana Rackov, Giorgia Iegiani, Daniel Uribe, Claudia Quezada, Cristóbal Belda-Iniesta, Carmen Escobedo-Lucea, Augusto Silva, Pere Puig, Víctor González-Rumayor, Ángel Ayuso-Sacido
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
Nilo1
antibody
glioblastoma
glioma stem cells
neural stem cells
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01665/full

Similar Items

Similar Items