Prenatal sonographic findings and management of placental mesenchymal dysplasia
Placental mesenchymal dysplasia (PMD) is a rare disorder of the placenta characterized by placentomegaly with diffuse hydropic stem villous, aneurysmally dilated vessels, and lack of trophoblastic proliferation. Case: The prenatal ultrasound of a 34-year-old woman (G1P0) at 33 weeks of gestation sho...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2021-04-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/48/2/10.31083/j.ceog.2021.02.2194 |
| _version_ | 1818552948680032256 |
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| author | Suchaya Luewan Pakorn Chaksuwat Tip Pongsuvareeyakul Theera Tongsong |
| author_facet | Suchaya Luewan Pakorn Chaksuwat Tip Pongsuvareeyakul Theera Tongsong |
| author_sort | Suchaya Luewan |
| collection | DOAJ |
| description | Placental mesenchymal dysplasia (PMD) is a rare disorder of the placenta characterized by placentomegaly with diffuse hydropic stem villous, aneurysmally dilated vessels, and lack of trophoblastic proliferation. Case: The prenatal ultrasound of a 34-year-old woman (G1P0) at 33 weeks of gestation showed an enlarged placenta with multiple cystic lesions, heterogeneous echoes with no active blood flow, and fetal growth restriction (FGR). The differential diagnosis involved partial mole, placental hemorrhage, and PMD. She developed preeclampsia at 38 weeks of gestation and gave birth to a normally formed, growth-restricted baby. The placenta, weighing 785 g, showed scattered cystic vesicles in the parenchyma. The histology shows enlarged edematous stem villi with occasional cistern formation and no area of chorioangioma or features of molar pregnancy. PMD associated fetal growth restriction was diagnosed. Conclusion: PMD has prenatal ultrasound result resembling those of partial mole, placental hemorrhage and chorioangioma, but the fetus is phenotypically normal. Nevertheless, fetal surveillance is essential. |
| first_indexed | 2024-12-12T09:19:44Z |
| format | Article |
| id | doaj.art-413a9fb0945b41779c42c0962f5c699a |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-12-12T09:19:44Z |
| publishDate | 2021-04-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-413a9fb0945b41779c42c0962f5c699a2022-12-22T00:29:15ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-04-0148243944310.31083/j.ceog.2021.02.2194S0390-6663(21)00106-8Prenatal sonographic findings and management of placental mesenchymal dysplasiaSuchaya Luewan0Pakorn Chaksuwat1Tip Pongsuvareeyakul2Theera Tongsong3Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, ThailandDepartment of Pathology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University, 50200 Chiang Mai, ThailandPlacental mesenchymal dysplasia (PMD) is a rare disorder of the placenta characterized by placentomegaly with diffuse hydropic stem villous, aneurysmally dilated vessels, and lack of trophoblastic proliferation. Case: The prenatal ultrasound of a 34-year-old woman (G1P0) at 33 weeks of gestation showed an enlarged placenta with multiple cystic lesions, heterogeneous echoes with no active blood flow, and fetal growth restriction (FGR). The differential diagnosis involved partial mole, placental hemorrhage, and PMD. She developed preeclampsia at 38 weeks of gestation and gave birth to a normally formed, growth-restricted baby. The placenta, weighing 785 g, showed scattered cystic vesicles in the parenchyma. The histology shows enlarged edematous stem villi with occasional cistern formation and no area of chorioangioma or features of molar pregnancy. PMD associated fetal growth restriction was diagnosed. Conclusion: PMD has prenatal ultrasound result resembling those of partial mole, placental hemorrhage and chorioangioma, but the fetus is phenotypically normal. Nevertheless, fetal surveillance is essential.https://www.imrpress.com/journal/CEOG/48/2/10.31083/j.ceog.2021.02.2194placental mesenchymal dysplasiaprenatal diagnosisultrasound |
| spellingShingle | Suchaya Luewan Pakorn Chaksuwat Tip Pongsuvareeyakul Theera Tongsong Prenatal sonographic findings and management of placental mesenchymal dysplasia Clinical and Experimental Obstetrics & Gynecology placental mesenchymal dysplasia prenatal diagnosis ultrasound |
| title | Prenatal sonographic findings and management of placental mesenchymal dysplasia |
| title_full | Prenatal sonographic findings and management of placental mesenchymal dysplasia |
| title_fullStr | Prenatal sonographic findings and management of placental mesenchymal dysplasia |
| title_full_unstemmed | Prenatal sonographic findings and management of placental mesenchymal dysplasia |
| title_short | Prenatal sonographic findings and management of placental mesenchymal dysplasia |
| title_sort | prenatal sonographic findings and management of placental mesenchymal dysplasia |
| topic | placental mesenchymal dysplasia prenatal diagnosis ultrasound |
| url | https://www.imrpress.com/journal/CEOG/48/2/10.31083/j.ceog.2021.02.2194 |
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