Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center

Increased HbA2 is a characteristic finding in minor beta thalassemia. Minor β-thalassemia is a heterozygote form of β-thalassemia that carries thalassemia genes but does not cause thalassemia disease. Diagnosis of carriers is done by CBC, RBC Index, and HbA2 test. Very few cases of people with minor...

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Main Authors: M Atapour, AR Zohoor, A Zolala, AR Arjmand
Format: Article
Language:English
Published: Kerman University of Medical Sciences 2003-03-01
Series:Journal of Kerman University of Medical Sciences
Subjects:
Online Access:https://jkmu.kmu.ac.ir/article_32887_49c6dce6c33afa29dfe92e06170dd046.pdf
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author M Atapour
AR Zohoor
A Zolala
AR Arjmand
author_facet M Atapour
AR Zohoor
A Zolala
AR Arjmand
author_sort M Atapour
collection DOAJ
description Increased HbA2 is a characteristic finding in minor beta thalassemia. Minor β-thalassemia is a heterozygote form of β-thalassemia that carries thalassemia genes but does not cause thalassemia disease. Diagnosis of carriers is done by CBC, RBC Index, and HbA2 test. Very few cases of people with minorthalassemia have a normal HbA2. According to the results of this pilot study it seams that percentage of minor thalassemia is noticeable in Kerman province. In this survey parents of thalassemia major and intermedia were evaluated. The result showed that about two percent of them had normal HbA2 . All of the people with normal HbA2 were born in Kerman. We suggest that this type of study should be done in different cities of this province in order to take necessary steps in effective prevention of major-thalassemia.
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spelling doaj.art-413ab39f7b8a476c9b7ece4c41ede3a82023-07-01T05:41:58ZengKerman University of Medical SciencesJournal of Kerman University of Medical Sciences2008-28432003-03-011029910432887Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease CenterM Atapour0AR Zohoor1A Zolala2AR Arjmand3Medical Laboratory Doctor, Kerman University of Medical Sciences and Health Services, Kerman, IranAssistant Professor of Epidemiology, Iran University of Medical Sciences and Health Services, Tehran, IranB.Sc. in Medical Laboratory ScienceM.Sc. Student of Hemathology, Tarbiat Moddares University, Tehran, IranIncreased HbA2 is a characteristic finding in minor beta thalassemia. Minor β-thalassemia is a heterozygote form of β-thalassemia that carries thalassemia genes but does not cause thalassemia disease. Diagnosis of carriers is done by CBC, RBC Index, and HbA2 test. Very few cases of people with minorthalassemia have a normal HbA2. According to the results of this pilot study it seams that percentage of minor thalassemia is noticeable in Kerman province. In this survey parents of thalassemia major and intermedia were evaluated. The result showed that about two percent of them had normal HbA2 . All of the people with normal HbA2 were born in Kerman. We suggest that this type of study should be done in different cities of this province in order to take necessary steps in effective prevention of major-thalassemia.https://jkmu.kmu.ac.ir/article_32887_49c6dce6c33afa29dfe92e06170dd046.pdfhba2minor thalassemia
spellingShingle M Atapour
AR Zohoor
A Zolala
AR Arjmand
Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center
Journal of Kerman University of Medical Sciences
hba2
minor thalassemia
title Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center
title_full Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center
title_fullStr Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center
title_full_unstemmed Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center
title_short Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center
title_sort evalution of hba2 in minor β thalassemia carriers reffered to kerman special disease center
topic hba2
minor thalassemia
url https://jkmu.kmu.ac.ir/article_32887_49c6dce6c33afa29dfe92e06170dd046.pdf
work_keys_str_mv AT matapour evalutionofhba2inminorbthalassemiacarriersrefferedtokermanspecialdiseasecenter
AT arzohoor evalutionofhba2inminorbthalassemiacarriersrefferedtokermanspecialdiseasecenter
AT azolala evalutionofhba2inminorbthalassemiacarriersrefferedtokermanspecialdiseasecenter
AT ararjmand evalutionofhba2inminorbthalassemiacarriersrefferedtokermanspecialdiseasecenter