Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels
In this work we describe the theory and 2D simulation of ion separation and focusing in a new concept of microfluidic separation device. The principle of the method of ion focusing is classical in the sense that it consists in opposing a hydrodynamic transport ensured by the solution flow to an elec...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Vilnius University Press
2012-10-01
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| Series: | Nonlinear Analysis |
| Subjects: | |
| Online Access: | http://www.journals.vu.lt/nonlinear-analysis/article/view/14049 |
| _version_ | 1828289056452116480 |
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| author | Oleksiy V. Klymenko Christian Amatore Wen Sun Yong-Liang Zhou Zhao-Wu Tian Irina Svir |
| author_facet | Oleksiy V. Klymenko Christian Amatore Wen Sun Yong-Liang Zhou Zhao-Wu Tian Irina Svir |
| author_sort | Oleksiy V. Klymenko |
| collection | DOAJ |
| description | In this work we describe the theory and 2D simulation of ion separation and focusing in a new concept of microfluidic separation device. The principle of the method of ion focusing is classical in the sense that it consists in opposing a hydrodynamic transport ensured by the solution flow to an electrophoretic driving force so that any ionic sample results poised within the microchannel at the point where the two forces equilibrate. The originality of the concept investigated here relies on the fact that thanks to the use of an ion-conducting membrane of variable thickness in electrical contact with the channel the electrophoretic force is varied continuously all along the channel length. Similarly, changing the geometric shape of the membrane allows a facile optimization of the device separation and focusing properties. |
| first_indexed | 2024-04-13T10:15:11Z |
| format | Article |
| id | doaj.art-413bcfa287c6445197c5caaf36aa15f4 |
| institution | Directory Open Access Journal |
| issn | 1392-5113 2335-8963 |
| language | English |
| last_indexed | 2024-04-13T10:15:11Z |
| publishDate | 2012-10-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Nonlinear Analysis |
| spelling | doaj.art-413bcfa287c6445197c5caaf36aa15f42022-12-22T02:50:45ZengVilnius University PressNonlinear Analysis1392-51132335-89632012-10-01174Theory and computational study of electrophoretic ion separation and focusing in microfluidic channelsOleksiy V. Klymenko0Christian Amatore1Wen Sun2Yong-Liang Zhou3Zhao-Wu Tian4Irina Svir5Ecole Normale Supérieure, FranceEcole Normale Supérieure, FranceXiamen University, ChinaXiamen University, ChinaXiamen University, ChinaEcole Normale Supérieure, FranceIn this work we describe the theory and 2D simulation of ion separation and focusing in a new concept of microfluidic separation device. The principle of the method of ion focusing is classical in the sense that it consists in opposing a hydrodynamic transport ensured by the solution flow to an electrophoretic driving force so that any ionic sample results poised within the microchannel at the point where the two forces equilibrate. The originality of the concept investigated here relies on the fact that thanks to the use of an ion-conducting membrane of variable thickness in electrical contact with the channel the electrophoretic force is varied continuously all along the channel length. Similarly, changing the geometric shape of the membrane allows a facile optimization of the device separation and focusing properties.http://www.journals.vu.lt/nonlinear-analysis/article/view/14049electrophoresisanalytical separationion-conducting membranes2D simulation |
| spellingShingle | Oleksiy V. Klymenko Christian Amatore Wen Sun Yong-Liang Zhou Zhao-Wu Tian Irina Svir Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels Nonlinear Analysis electrophoresis analytical separation ion-conducting membranes 2D simulation |
| title | Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels |
| title_full | Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels |
| title_fullStr | Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels |
| title_full_unstemmed | Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels |
| title_short | Theory and computational study of electrophoretic ion separation and focusing in microfluidic channels |
| title_sort | theory and computational study of electrophoretic ion separation and focusing in microfluidic channels |
| topic | electrophoresis analytical separation ion-conducting membranes 2D simulation |
| url | http://www.journals.vu.lt/nonlinear-analysis/article/view/14049 |
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