Identifying polymorphic cis-regulatory variants as risk markers for lung carcinogenesis and chemotherapy responses in tobacco smokers from eastern India

Identifying polymorphic cis-regulatory variants as risk markers for lung carcinogenesis and chemotherapy responses in tobacco smokers from eastern India

Abstract Aberrant expression of xenobiotic metabolism and DNA repair genes is critical to lung cancer pathogenesis. This study aims to identify the cis-regulatory variants of the genes modulating lung cancer risk among tobacco smokers and altering their chemotherapy responses. From a list of 2984 SN...

Full description

Bibliographic Details
Main Authors: Debmalya Sengupta, Pramiti Mukhopadhyay, Souradeep Banerjee, Kausik Ganguly, Prateek Mascharak, Noyonika Mukherjee, Sangeeta Mitra, Samsiddhi Bhattacharjee, Ritabrata Mitra, Abhijit Sarkar, Tamohan Chaudhuri, Gautam Bhattacharjee, Somsubhra Nath, Susanta Roychoudhury, Mainak Sengupta
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30962-9

Internet

https://doi.org/10.1038/s41598-023-30962-9

Similar Items