Acute Kidney Injury after Transcatheter Aortic Valve Implantation
Aim. The aim of the study was to evaluate the incidence and predictors of acute kidney injury (AKI) associated with transcatheter aortic valve implantation (TAVI).Material and methods. 50 patients (39 women, 11 men) aged 76 (71; 80) years who underwent TAVI were examined. One day after TAVI, blood c...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2022-07-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/2747 |
| _version_ | 1826949509315297280 |
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| author | L. V. Kremneva L. I. Gapon S. V. Shalaev D. V. Krasheninin |
| author_facet | L. V. Kremneva L. I. Gapon S. V. Shalaev D. V. Krasheninin |
| author_sort | L. V. Kremneva |
| collection | DOAJ |
| description | Aim. The aim of the study was to evaluate the incidence and predictors of acute kidney injury (AKI) associated with transcatheter aortic valve implantation (TAVI).Material and methods. 50 patients (39 women, 11 men) aged 76 (71; 80) years who underwent TAVI were examined. One day after TAVI, blood creatinine level was determined by the Jaffe method and troponin I by a highly sensitive method (hs-cTnI). Acute kidney injury (AKI) was diagnosed according to the KDIGO criteria (2012). The following hospital complications were evaluated: cases of cardiac death, intraoperative myocardial infarction (MI), stroke and transient ischemic attack, permanent pacemaker implantation, recurrent paroxysms of atrial fibrillation.Results. History of MI had 22% of patients, percutaneous coronary intervention – 38%, hypertension – 98%, chronic kidney disease – 48%, diabetes mellitus – 24%, class II NYHA of chronic heart failure (CHF) – 52%, NYHA class III – 46%, NYHA class IV – 2%. The risk of operational mortality according to EuroSCORE II was 6.3±5.4%. AKI after TAVI was registered in 6 (12%) patients (1 grade AKI – 8%, 2 grade – 2%, 3 grade – 2%). Parameters associated with AKI after TAVI were higher CHF NYHA class (p=0,020), high hs-cTnI level (p=0,013), intraoperative MI (p=0.035). The predictor of AKI after TAVI was high hs-cTnI level (odds ratio 4.0, 95% confidence interval 1.0-16.1). Among patients with AKI after TAVI in compare with patients without AKI, the cumulative frequency of cardiac death, MI, strokes and transient ischemic attacks, implantation of a permanent pacemaker, the proportion of people with paroxysmal atrial fibrillation during the hospital stay was 5,8 times higher (66.7% vs 11.4% respectively, p=0.001).Conclusion. AKI after TAVI was present in 12% of patients. The predictor for AKI development was an increase in hs-cTnI level after TAVI implantation. The hospital prognosis after TAVI is worse in patients with postoperative AKI. |
| first_indexed | 2024-03-08T13:59:55Z |
| format | Article |
| id | doaj.art-41412b90b4dd41ec960df26fd670547d |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2025-02-17T22:14:22Z |
| publishDate | 2022-07-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-41412b90b4dd41ec960df26fd670547d2024-12-04T11:48:21ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532022-07-0118326126710.20996/1819-6446-2022-06-102025Acute Kidney Injury after Transcatheter Aortic Valve ImplantationL. V. Kremneva0L. I. Gapon1S. V. Shalaev2D. V. Krasheninin3Tyumen State Medical University; Tyumen Cardiology Research Center – Branch of the Tomsk National Research Medical Center of the Russian Academy of SciencesTyumen Cardiology Research Center – Branch of the Tomsk National Research Medical Center of the Russian Academy of SciencesTyumen State Medical UniversityTyumen State Medical UniversityAim. The aim of the study was to evaluate the incidence and predictors of acute kidney injury (AKI) associated with transcatheter aortic valve implantation (TAVI).Material and methods. 50 patients (39 women, 11 men) aged 76 (71; 80) years who underwent TAVI were examined. One day after TAVI, blood creatinine level was determined by the Jaffe method and troponin I by a highly sensitive method (hs-cTnI). Acute kidney injury (AKI) was diagnosed according to the KDIGO criteria (2012). The following hospital complications were evaluated: cases of cardiac death, intraoperative myocardial infarction (MI), stroke and transient ischemic attack, permanent pacemaker implantation, recurrent paroxysms of atrial fibrillation.Results. History of MI had 22% of patients, percutaneous coronary intervention – 38%, hypertension – 98%, chronic kidney disease – 48%, diabetes mellitus – 24%, class II NYHA of chronic heart failure (CHF) – 52%, NYHA class III – 46%, NYHA class IV – 2%. The risk of operational mortality according to EuroSCORE II was 6.3±5.4%. AKI after TAVI was registered in 6 (12%) patients (1 grade AKI – 8%, 2 grade – 2%, 3 grade – 2%). Parameters associated with AKI after TAVI were higher CHF NYHA class (p=0,020), high hs-cTnI level (p=0,013), intraoperative MI (p=0.035). The predictor of AKI after TAVI was high hs-cTnI level (odds ratio 4.0, 95% confidence interval 1.0-16.1). Among patients with AKI after TAVI in compare with patients without AKI, the cumulative frequency of cardiac death, MI, strokes and transient ischemic attacks, implantation of a permanent pacemaker, the proportion of people with paroxysmal atrial fibrillation during the hospital stay was 5,8 times higher (66.7% vs 11.4% respectively, p=0.001).Conclusion. AKI after TAVI was present in 12% of patients. The predictor for AKI development was an increase in hs-cTnI level after TAVI implantation. The hospital prognosis after TAVI is worse in patients with postoperative AKI.https://www.rpcardio.online/jour/article/view/2747transcatheter aortic valve implantationacute kidney injuryhospital outcomes |
| spellingShingle | L. V. Kremneva L. I. Gapon S. V. Shalaev D. V. Krasheninin Acute Kidney Injury after Transcatheter Aortic Valve Implantation Рациональная фармакотерапия в кардиологии transcatheter aortic valve implantation acute kidney injury hospital outcomes |
| title | Acute Kidney Injury after Transcatheter Aortic Valve Implantation |
| title_full | Acute Kidney Injury after Transcatheter Aortic Valve Implantation |
| title_fullStr | Acute Kidney Injury after Transcatheter Aortic Valve Implantation |
| title_full_unstemmed | Acute Kidney Injury after Transcatheter Aortic Valve Implantation |
| title_short | Acute Kidney Injury after Transcatheter Aortic Valve Implantation |
| title_sort | acute kidney injury after transcatheter aortic valve implantation |
| topic | transcatheter aortic valve implantation acute kidney injury hospital outcomes |
| url | https://www.rpcardio.online/jour/article/view/2747 |
| work_keys_str_mv | AT lvkremneva acutekidneyinjuryaftertranscatheteraorticvalveimplantation AT ligapon acutekidneyinjuryaftertranscatheteraorticvalveimplantation AT svshalaev acutekidneyinjuryaftertranscatheteraorticvalveimplantation AT dvkrasheninin acutekidneyinjuryaftertranscatheteraorticvalveimplantation |