INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS

INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS

Two in vivo metabolic challenges were conducted to assess the changes in glucose metabolism during three intervals prepartum (-6, -4, -2 weeks) and three postpartum (+2, +4, +6 weeks) in six multiparous pregnant Nubian goats. Challenges consisted of intravenous administration of 1) glucose (62.5 g/g...

Full description

Bibliographic Details
Main Authors: J. Chávez, Guadalupe Bernal, A. Rodríguez, K. Mark, E. Díaz, A. Aguilera, T. Reis de Souza, C. Betancourt, M. Cárdenas
Format: Article
Language:English
Published: Universidad Autónoma de Yucatán 2009-06-01
Series:Tropical and Subtropical Agroecosystems
Subjects:
Energy metabolism, dairy goat, metabolic challenge, glucose, insulin, NEFA.
Online Access:http://www.revista.ccba.uady.mx/ojs/index.php/TSA/article/view/66
_version_ 1811230357991718912
author J. Chávez
Guadalupe Bernal
A. Rodríguez
K. Mark
E. Díaz
A. Aguilera
T. Reis de Souza
C. Betancourt
M. Cárdenas
author_facet J. Chávez
Guadalupe Bernal
A. Rodríguez
K. Mark
E. Díaz
A. Aguilera
T. Reis de Souza
C. Betancourt
M. Cárdenas
author_sort J. Chávez
collection DOAJ
description Two in vivo metabolic challenges were conducted to assess the changes in glucose metabolism during three intervals prepartum (-6, -4, -2 weeks) and three postpartum (+2, +4, +6 weeks) in six multiparous pregnant Nubian goats. Challenges consisted of intravenous administration of 1) glucose (62.5 g/goat) and 2) L-epinephrine (0.7 mg/kg body weight). Blood samples were collected via jugular cannula from 30 min pre-injection (basal concentrations) to four hours post-injection. Response variables for glucose challenge were glucose concentration at zero time (to) glucose disappearance rate (t½), insulin and NEFA concentrations; for the epinephrine challenge glucose, NEFA and insulin integrated responses were determined through the four hours of sampling. Data were analyzed according to a repeated-measures design. Dry matter intakes (1.8±0.07 kg/d) were not different throughout the study (P>0.1). Average milk production (649±69 g/d) was not different among periods (P>0.1). Basal glucose and insulin concentrations were not different (P>0.1) between pregnancy and lactation, with means (± standard error) of 77.9±3.7mg/dl, and 0.264±.034ng/dl, respectively. Basal NEFA concentrations were greater (P0.1) and for t½ of 31±15 min (P>0.1). Insulin responses were similar for all periods (63.3±8.2 ngml-1min) (P>0.1). The epinephrine challenge resulted in similar changes in glucose and insulin integrated responses throughout the periods evaluated (P>0.1), with corresponding means for glucose of 3886.5±318 mgml-1min, and 21.6±7.7 ngml-1min, but elicited a significant (P
first_indexed 2024-04-12T10:28:03Z
format Article
id doaj.art-4143269971314f85a19cd1a74b7bcdd5
institution Directory Open Access Journal
issn 1870-0462
language English
last_indexed 2024-04-12T10:28:03Z
publishDate 2009-06-01
publisher Universidad Autónoma de Yucatán
record_format Article
series Tropical and Subtropical Agroecosystems
spelling doaj.art-4143269971314f85a19cd1a74b7bcdd52022-12-22T03:36:55ZengUniversidad Autónoma de YucatánTropical and Subtropical Agroecosystems1870-04622009-06-0111122523282INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATSJ. Chávez0Guadalupe Bernal1A. Rodríguez2K. Mark3E. Díaz4A. Aguilera5T. Reis de Souza6C. Betancourt7M. Cárdenas8Facultad de Ciencias Naturales, Universidad Autónoma de QuerétaroUniversidad Autónoma de QuerétaroFacultad de Ciencias Naturales, Universidad Autónoma de QuerétaroFacultad de Ciencias Naturales, Universidad Autónoma de QuerétaroInstituto Nacional de la Nutrición-Salvador ZubiránFacultad de Ciencias Naturales, Universidad Autónoma de QuerétaroFacultad de Ciencias Naturales, Universidad Autónoma de QuerétaroFacultad de Ciencias Naturales, Universidad Autónoma de QuerétaroInstituto Nacional de la Nutrición-Salvador ZubiránTwo in vivo metabolic challenges were conducted to assess the changes in glucose metabolism during three intervals prepartum (-6, -4, -2 weeks) and three postpartum (+2, +4, +6 weeks) in six multiparous pregnant Nubian goats. Challenges consisted of intravenous administration of 1) glucose (62.5 g/goat) and 2) L-epinephrine (0.7 mg/kg body weight). Blood samples were collected via jugular cannula from 30 min pre-injection (basal concentrations) to four hours post-injection. Response variables for glucose challenge were glucose concentration at zero time (to) glucose disappearance rate (t½), insulin and NEFA concentrations; for the epinephrine challenge glucose, NEFA and insulin integrated responses were determined through the four hours of sampling. Data were analyzed according to a repeated-measures design. Dry matter intakes (1.8±0.07 kg/d) were not different throughout the study (P>0.1). Average milk production (649±69 g/d) was not different among periods (P>0.1). Basal glucose and insulin concentrations were not different (P>0.1) between pregnancy and lactation, with means (± standard error) of 77.9±3.7mg/dl, and 0.264±.034ng/dl, respectively. Basal NEFA concentrations were greater (P0.1) and for t½ of 31±15 min (P>0.1). Insulin responses were similar for all periods (63.3±8.2 ngml-1min) (P>0.1). The epinephrine challenge resulted in similar changes in glucose and insulin integrated responses throughout the periods evaluated (P>0.1), with corresponding means for glucose of 3886.5±318 mgml-1min, and 21.6±7.7 ngml-1min, but elicited a significant (Phttp://www.revista.ccba.uady.mx/ojs/index.php/TSA/article/view/66Energy metabolism, dairy goat, metabolic challenge, glucose, insulin, NEFA.
spellingShingle J. Chávez
Guadalupe Bernal
A. Rodríguez
K. Mark
E. Díaz
A. Aguilera
T. Reis de Souza
C. Betancourt
M. Cárdenas
INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS
Tropical and Subtropical Agroecosystems
Energy metabolism, dairy goat, metabolic challenge, glucose, insulin, NEFA.
title INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS
title_full INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS
title_fullStr INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS
title_full_unstemmed INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS
title_short INFLUENCE OF PREGNANCY AND LACTATION ON GLUCOSE METABOLISM OF NUBIAN GOATS
title_sort influence of pregnancy and lactation on glucose metabolism of nubian goats
topic Energy metabolism, dairy goat, metabolic challenge, glucose, insulin, NEFA.
url http://www.revista.ccba.uady.mx/ojs/index.php/TSA/article/view/66
work_keys_str_mv AT jchavez influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT guadalupebernal influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT arodraguez influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT kmark influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT edaaz influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT aaguilera influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT treisdesouza influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT cbetancourt influenceofpregnancyandlactationonglucosemetabolismofnubiangoats
AT mcardenas influenceofpregnancyandlactationonglucosemetabolismofnubiangoats

Similar Items