Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorder
IntroductionPsychotic disorders such schizophrenia and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders with social cognitive deficits. Specifically, biased interpretation of social information can result in interpersonal difficulties. Cognitive biases are prevalent i...
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1127535/full |
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| author | Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Angel Cabezas Angel Cabezas Angel Cabezas Angel Cabezas Nuria Manzanares Nuria Manzanares Montse Sole Montse Sole Montse Sole Montse Sole Lia Corral Lia Corral Lia Corral Lia Corral Elisabet Vilella Elisabet Vilella Elisabet Vilella Elisabet Vilella Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes |
| author_facet | Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Angel Cabezas Angel Cabezas Angel Cabezas Angel Cabezas Nuria Manzanares Nuria Manzanares Montse Sole Montse Sole Montse Sole Montse Sole Lia Corral Lia Corral Lia Corral Lia Corral Elisabet Vilella Elisabet Vilella Elisabet Vilella Elisabet Vilella Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes |
| author_sort | Vanessa Sanchez-Gistau |
| collection | DOAJ |
| description | IntroductionPsychotic disorders such schizophrenia and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders with social cognitive deficits. Specifically, biased interpretation of social information can result in interpersonal difficulties. Cognitive biases are prevalent in psychosis, but no previous study has investigated whether the type and severity of cognitive biases differ between subjects experiencing first-episode psychosis (FEP) with (FEP-ADHD+) and without ADHD (FEP-ADHD−).MethodsA total of 121 FEP outpatients at the Early Intervention Service of Reus were screened for childhood ADHD through the Diagnostic Interview for ADHD (DIVA). Cognitive biases were assessed by the Cognitive Biases Questionnaire for Psychosis (CBQp). CBQp scores of FEPs groups were compared with those of healthy controls (HCs) with an analysis of covariance. Spearman correlation analysis explored associations between CBQp scores and psychopathology.ResultsThirty-one FEPs met the criteria for childhood ADHD and reported significantly more cognitive bias [median (interquartile range): 47 (38–56)] than FEP-ADHD− [42 (37–48)] and HCs [38 (35.5–43)]. CBQp scores did not differ between FEP-ADHD-and HCs when adjusted for age and sex. After controlling for clinical differences, Intentionalising (F = 20.97; p < 0.001) and Emotional Reasoning biases (F = 4.17; p = 0.04) were more strongly associated with FEP-ADHD+ than FEP-ADHD−. Cognitive biases were significantly correlated with positive psychotic symptoms in both groups but only with depressive symptoms in FEP-ADHD− (r = 0.258; p = 0.03) and with poor functioning in FEP-ADHD+ (r = −0.504; p = 0.003).ConclusionCognitive bias severity increased from HCs to FEP-ADHD-patients to FEP-ADHD+ patients. FEP-ADHD+ patients may be a particularly vulnerable group in which metacognitive targeted interventions are needed. |
| first_indexed | 2024-03-13T01:11:33Z |
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| language | English |
| last_indexed | 2024-03-13T01:11:33Z |
| publishDate | 2023-07-01 |
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| series | Frontiers in Psychology |
| spelling | doaj.art-41438f627d284c16aa504e63ed9d4d1d2023-07-05T21:59:20ZengFrontiers Media S.A.Frontiers in Psychology1664-10782023-07-011410.3389/fpsyg.2023.11275351127535Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorderVanessa Sanchez-Gistau0Vanessa Sanchez-Gistau1Vanessa Sanchez-Gistau2Vanessa Sanchez-Gistau3Angel Cabezas4Angel Cabezas5Angel Cabezas6Angel Cabezas7Nuria Manzanares8Nuria Manzanares9Montse Sole10Montse Sole11Montse Sole12Montse Sole13Lia Corral14Lia Corral15Lia Corral16Lia Corral17Elisabet Vilella18Elisabet Vilella19Elisabet Vilella20Elisabet Vilella21Alfonso Gutierrez-Zotes22Alfonso Gutierrez-Zotes23Alfonso Gutierrez-Zotes24Alfonso Gutierrez-Zotes25Hospital Universitari Institut Pere Mata of Reus, Reus, SpainInstitut d’Investigació Sanitària Pere Virgili (IISPV- CERCA), Tarragona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, Madrid, SpainUniversitat Rovira i Virgili (URV), Reus, SpainHospital Universitari Institut Pere Mata of Reus, Reus, SpainInstitut d’Investigació Sanitària Pere Virgili (IISPV- CERCA), Tarragona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, Madrid, SpainUniversitat Rovira i Virgili (URV), Reus, SpainHospital Universitari Institut Pere Mata of Reus, Reus, SpainUniversitat Rovira i Virgili (URV), Reus, SpainHospital Universitari Institut Pere Mata of Reus, Reus, SpainInstitut d’Investigació Sanitària Pere Virgili (IISPV- CERCA), Tarragona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, Madrid, SpainUniversitat Rovira i Virgili (URV), Reus, SpainHospital Universitari Institut Pere Mata of Reus, Reus, SpainInstitut d’Investigació Sanitària Pere Virgili (IISPV- CERCA), Tarragona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, Madrid, SpainUniversitat Rovira i Virgili (URV), Reus, SpainHospital Universitari Institut Pere Mata of Reus, Reus, SpainInstitut d’Investigació Sanitària Pere Virgili (IISPV- CERCA), Tarragona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, Madrid, SpainUniversitat Rovira i Virgili (URV), Reus, SpainHospital Universitari Institut Pere Mata of Reus, Reus, SpainInstitut d’Investigació Sanitària Pere Virgili (IISPV- CERCA), Tarragona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, Madrid, SpainUniversitat Rovira i Virgili (URV), Reus, SpainIntroductionPsychotic disorders such schizophrenia and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders with social cognitive deficits. Specifically, biased interpretation of social information can result in interpersonal difficulties. Cognitive biases are prevalent in psychosis, but no previous study has investigated whether the type and severity of cognitive biases differ between subjects experiencing first-episode psychosis (FEP) with (FEP-ADHD+) and without ADHD (FEP-ADHD−).MethodsA total of 121 FEP outpatients at the Early Intervention Service of Reus were screened for childhood ADHD through the Diagnostic Interview for ADHD (DIVA). Cognitive biases were assessed by the Cognitive Biases Questionnaire for Psychosis (CBQp). CBQp scores of FEPs groups were compared with those of healthy controls (HCs) with an analysis of covariance. Spearman correlation analysis explored associations between CBQp scores and psychopathology.ResultsThirty-one FEPs met the criteria for childhood ADHD and reported significantly more cognitive bias [median (interquartile range): 47 (38–56)] than FEP-ADHD− [42 (37–48)] and HCs [38 (35.5–43)]. CBQp scores did not differ between FEP-ADHD-and HCs when adjusted for age and sex. After controlling for clinical differences, Intentionalising (F = 20.97; p < 0.001) and Emotional Reasoning biases (F = 4.17; p = 0.04) were more strongly associated with FEP-ADHD+ than FEP-ADHD−. Cognitive biases were significantly correlated with positive psychotic symptoms in both groups but only with depressive symptoms in FEP-ADHD− (r = 0.258; p = 0.03) and with poor functioning in FEP-ADHD+ (r = −0.504; p = 0.003).ConclusionCognitive bias severity increased from HCs to FEP-ADHD-patients to FEP-ADHD+ patients. FEP-ADHD+ patients may be a particularly vulnerable group in which metacognitive targeted interventions are needed.https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1127535/fullcognitive biasCBQpADHDfirst episode psychosis (FEP)schizophreniasocial cognition |
| spellingShingle | Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Vanessa Sanchez-Gistau Angel Cabezas Angel Cabezas Angel Cabezas Angel Cabezas Nuria Manzanares Nuria Manzanares Montse Sole Montse Sole Montse Sole Montse Sole Lia Corral Lia Corral Lia Corral Lia Corral Elisabet Vilella Elisabet Vilella Elisabet Vilella Elisabet Vilella Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes Alfonso Gutierrez-Zotes Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorder Frontiers in Psychology cognitive bias CBQp ADHD first episode psychosis (FEP) schizophrenia social cognition |
| title | Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorder |
| title_full | Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorder |
| title_fullStr | Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorder |
| title_full_unstemmed | Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorder |
| title_short | Cognitive biases in first-episode psychosis with and without attention-deficit/hyperactivity disorder |
| title_sort | cognitive biases in first episode psychosis with and without attention deficit hyperactivity disorder |
| topic | cognitive bias CBQp ADHD first episode psychosis (FEP) schizophrenia social cognition |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1127535/full |
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