The use of hyaluronic acid based dressings to treat burns: A review

Deep cutaneous lesions such as burns, traumas or ulcers are all conditions characterized by a massive loss of dermis, bringing several important consequences. For the treatment of these conditions, the evolution of material science has made available new dressings based on natural and synthetic poly...

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Main Author: Cristina Longinotti
Format: Article
Language:English
Published: Oxford University Press 2014-10-01
Series:Burns & Trauma
Subjects:
Online Access:http://www.burnstrauma.com/article.asp?issn=2321-3868;year=2014;volume=2;issue=4;spage=162;epage=168;aulast=Longinotti
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author Cristina Longinotti
author_facet Cristina Longinotti
author_sort Cristina Longinotti
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description Deep cutaneous lesions such as burns, traumas or ulcers are all conditions characterized by a massive loss of dermis, bringing several important consequences. For the treatment of these conditions, the evolution of material science has made available new dressings based on natural and synthetic polymers. Hyaluronic acid (HA) is involved in many steps of the wound healing process, such as inflammation, granulation and re-epithelialization. In order to overcome the poor physical properties of the native polymer, such as solubility and rapid degradation, insoluble molecules starting from the natural compound were produced via esterification. Thanks to their improved structural properties, the dressings based on these hyaluronic acid derivatives represent a valuable ­option for the treatment of deep burns. This narrative monograph describes the development and the outcome of the use of these products in burns. The currently available clinical experience suggests that these HA medical devices represent a safe therapeutic method useful for the treatment of acute wounds.
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spelling doaj.art-4147645b9c9c44f0ae7d903887194b8e2022-12-21T22:46:33ZengOxford University PressBurns & Trauma2321-38682321-38762014-10-012416216810.4103/2321-3868.142398The use of hyaluronic acid based dressings to treat burns: A reviewCristina LonginottiDeep cutaneous lesions such as burns, traumas or ulcers are all conditions characterized by a massive loss of dermis, bringing several important consequences. For the treatment of these conditions, the evolution of material science has made available new dressings based on natural and synthetic polymers. Hyaluronic acid (HA) is involved in many steps of the wound healing process, such as inflammation, granulation and re-epithelialization. In order to overcome the poor physical properties of the native polymer, such as solubility and rapid degradation, insoluble molecules starting from the natural compound were produced via esterification. Thanks to their improved structural properties, the dressings based on these hyaluronic acid derivatives represent a valuable ­option for the treatment of deep burns. This narrative monograph describes the development and the outcome of the use of these products in burns. The currently available clinical experience suggests that these HA medical devices represent a safe therapeutic method useful for the treatment of acute wounds.http://www.burnstrauma.com/article.asp?issn=2321-3868;year=2014;volume=2;issue=4;spage=162;epage=168;aulast=LonginottiBurnshyaluronic acid
spellingShingle Cristina Longinotti
The use of hyaluronic acid based dressings to treat burns: A review
Burns & Trauma
Burns
hyaluronic acid
title The use of hyaluronic acid based dressings to treat burns: A review
title_full The use of hyaluronic acid based dressings to treat burns: A review
title_fullStr The use of hyaluronic acid based dressings to treat burns: A review
title_full_unstemmed The use of hyaluronic acid based dressings to treat burns: A review
title_short The use of hyaluronic acid based dressings to treat burns: A review
title_sort use of hyaluronic acid based dressings to treat burns a review
topic Burns
hyaluronic acid
url http://www.burnstrauma.com/article.asp?issn=2321-3868;year=2014;volume=2;issue=4;spage=162;epage=168;aulast=Longinotti
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