Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced by ischemia and reperfusion

Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced by ischemia and reperfusion

Abstract Purpose: To evaluate the cardioprotective response of the pharmacological modulation of β-adrenergic receptors (β-AR) in animal model of cardiac ischemia and reperfusion (CIR), in spontaneously hypertensive (SHR) and normotensive (NWR) rats. Methods: CIR was induced by the occlusion of l...

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Bibliographic Details
Main Authors: Francisco Sandro Menezes-Rodrigues, Paolo Ruggero Errante, José Gustavo Padrão Tavares, Renato Ribeiro Nogueira Ferraz, Walter José Gomes, Murched Omar Taha, Carla Alessandra Scorza, Fúlvio Alexandre Scorza, Afonso Caricati-Neto
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019-06-01
Series:Acta Cirúrgica Brasileira
Subjects:
Cardiovascular Diseases
Myocardial Ischemia
Reperfusion
Receptors, Adrenergic
Drug Therapy
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502019000500204&tlng=en

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