Corticosterone as a Potential Confounding Factor in Delineating Mechanisms Underlying Ketamine’s Rapid Antidepressant Actions

Corticosterone as a Potential Confounding Factor in Delineating Mechanisms Underlying Ketamine’s Rapid Antidepressant Actions

Recent research into the rapid antidepressant effect of subanesthetic doses of ketamine have identified a series of relevant protein cascades activated within hours of administration. Prior to, or concurrent with, these activation cascades, ketamine treatment generates dissociative and psychotomimet...

Full description

Bibliographic Details
Main Authors: Lauren Wegman-Points, Brock Pope, Allison Zobel-Mask, Lori Winter, Eric Wauson, Vanja Duric, Li-Lian Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
ketamine
hydroxynorketamine
glucocorticoids
corticosterone
rapid-acting antidepressant
stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.590221/full

Similar Items

Similar Items