ACE2 as a Therapeutic Target for COVID-19; Its Role in Infectious Processes and Regulation by Modulators of the RAAS System

ACE2 as a Therapeutic Target for COVID-19; Its Role in Infectious Processes and Regulation by Modulators of the RAAS System

Angiotensin converting enzyme 2 (ACE2) is the recognized host cell receptor responsible for mediating infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ACE2 bound to tissue facilitates infectivity of SARS-CoV-2; thus, one could argue that decreasing ACE2 tissue expression wo...

Full description

Bibliographic Details
Main Authors: Veronique Michaud, Malavika Deodhar, Meghan Arwood, Sweilem B Al Rihani, Pamela Dow, Jacques Turgeon
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Clinical Medicine
Subjects:
ACE2
SARS-CoV-2
renin-angiotensin-aldosterone system
angiotensin II converting enzyme inhibitors
angiotensin II type 1 receptor blockers
pneumonia
Online Access:https://www.mdpi.com/2077-0383/9/7/2096

Similar Items

Similar Items