Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction
Background: Coronary Artery Disease (CAD) is the leading cause of morbidity and mortality all around the world. Red cell distribution width (RDW) is an indicator for the variability and size of circulating erythrocytes, has recently been shown to be an independent predictor of prognosis in patients...
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| Format: | Article |
| Language: | English |
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South Valley University, Faculty of Medicine
2021-08-01
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| Series: | SVU - International Journal of Medical Sciences |
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| Online Access: | https://svuijm.journals.ekb.eg/article_158421.html |
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| author | Mai Ahmed Hamza Mohammed Mahmoud Mahmoud Abd-el Ghaffar Ahmed El-Tayeb |
| author_facet | Mai Ahmed Hamza Mohammed Mahmoud Mahmoud Abd-el Ghaffar Ahmed El-Tayeb |
| author_sort | Mai Ahmed Hamza |
| collection | DOAJ |
| description | Background: Coronary Artery Disease (CAD) is the leading cause of morbidity and mortality all around the world. Red cell distribution width (RDW) is an indicator for the variability and size of circulating erythrocytes, has recently been shown to be an independent predictor of prognosis in patients with cardiovascular disease.
Objectives:to assess the relationship between RDW and severity of coronary artery disease (CAD) by SYNTAX score in patients with ST-elevation myocardial infarction (STEMI) undergoing coronary angiography.
Methods:Eighty consecutive patientswho underwent coronary angiography after diagnosis of STEMI, were enrolled in this study which was conducted at cardiology department of Qena university hospital and Qena general hospital at period from October 2018 to July 2019.
Results: there was no statistical significant difference (p-value > 0.05) between normal RDW patients and Abnormal RDW patients as regard demographic data(age, sex, BMI, smoking, HTN, dyslipidemia) except for DM, there was statistical significant difference, also there was no statistical significant difference (p-value > 0.05) between normal RDW patients and Abnormal RDW patients as regard laboratory data (eGFR,WBCs, neutrophils, lymphocytes,N/L ratio). While there was statistically significant difference (p-value < 0.05) between normal RDW patients and Abnormal RDW patients as regard LVEF, SWMA, number of affected vessels and SYNTAX score.
After adjusting for all correlates, patients was high syntax scores were 3.6 times more liable for having abnormal RDW class (AOR=3.6, 95% CI: 1.2–7.3, p-value =0.029).
Conclusion:Red cell distribution width is positively correlated with number of diseased vessels and high syntax score and extent of coronary artery disease. |
| first_indexed | 2024-12-13T01:10:09Z |
| format | Article |
| id | doaj.art-414bccfa50ac49f28fafdbd8db7f3bc7 |
| institution | Directory Open Access Journal |
| issn | 2735-427X 2636-3402 |
| language | English |
| last_indexed | 2024-12-13T01:10:09Z |
| publishDate | 2021-08-01 |
| publisher | South Valley University, Faculty of Medicine |
| record_format | Article |
| series | SVU - International Journal of Medical Sciences |
| spelling | doaj.art-414bccfa50ac49f28fafdbd8db7f3bc72022-12-22T00:04:30ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022021-08-0142113https://dx.doi.org/10.21608/svuijm.2021.64583.1100 Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial InfarctionMai Ahmed Hamza0Mohammed Mahmoud1 Mahmoud Abd-el Ghaffar2 Ahmed El-Tayeb3Department of cardiology, Faculty of Medicine, Al-Azhar university (Assiut branch), EgyptDepartment of cardiology, Faculty of Medicine, Al-Azhar university (Assiut branch), EgyptDepartment of cardiology, Faculty of Medicine, Al-Azhar university (Assiut branch), EgyptDepartment of cardiology, Faculty of Medicine, Al-Azhar university (Assiut branch), EgyptBackground: Coronary Artery Disease (CAD) is the leading cause of morbidity and mortality all around the world. Red cell distribution width (RDW) is an indicator for the variability and size of circulating erythrocytes, has recently been shown to be an independent predictor of prognosis in patients with cardiovascular disease. Objectives:to assess the relationship between RDW and severity of coronary artery disease (CAD) by SYNTAX score in patients with ST-elevation myocardial infarction (STEMI) undergoing coronary angiography. Methods:Eighty consecutive patientswho underwent coronary angiography after diagnosis of STEMI, were enrolled in this study which was conducted at cardiology department of Qena university hospital and Qena general hospital at period from October 2018 to July 2019. Results: there was no statistical significant difference (p-value > 0.05) between normal RDW patients and Abnormal RDW patients as regard demographic data(age, sex, BMI, smoking, HTN, dyslipidemia) except for DM, there was statistical significant difference, also there was no statistical significant difference (p-value > 0.05) between normal RDW patients and Abnormal RDW patients as regard laboratory data (eGFR,WBCs, neutrophils, lymphocytes,N/L ratio). While there was statistically significant difference (p-value < 0.05) between normal RDW patients and Abnormal RDW patients as regard LVEF, SWMA, number of affected vessels and SYNTAX score. After adjusting for all correlates, patients was high syntax scores were 3.6 times more liable for having abnormal RDW class (AOR=3.6, 95% CI: 1.2–7.3, p-value =0.029). Conclusion:Red cell distribution width is positively correlated with number of diseased vessels and high syntax score and extent of coronary artery disease.https://svuijm.journals.ekb.eg/article_158421.htmlst-elevation myocardial infarction (stemi); red blood cell distribution width(rdw); syntax score; atherosclerosis |
| spellingShingle | Mai Ahmed Hamza Mohammed Mahmoud Mahmoud Abd-el Ghaffar Ahmed El-Tayeb Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction SVU - International Journal of Medical Sciences st-elevation myocardial infarction (stemi); red blood cell distribution width(rdw); syntax score; atherosclerosis |
| title | Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction |
| title_full | Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction |
| title_fullStr | Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction |
| title_full_unstemmed | Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction |
| title_short | Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction |
| title_sort | relationship between red blood cell distribution width and extent of coronary artery disease in patient with st elevation myocardial infarction |
| topic | st-elevation myocardial infarction (stemi); red blood cell distribution width(rdw); syntax score; atherosclerosis |
| url | https://svuijm.journals.ekb.eg/article_158421.html |
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