Single-Cell Transcriptome Reveals the Metabolic and Clinical Features of a Highly Malignant Cell Subpopulation in Pancreatic Ductal Adenocarcinoma

Single-Cell Transcriptome Reveals the Metabolic and Clinical Features of a Highly Malignant Cell Subpopulation in Pancreatic Ductal Adenocarcinoma

Background: Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with a high mortality rate. PDAC exhibits significant heterogeneity as well as alterations in metabolic pathways that are associated with its malignant progression. In this study, we explored the metabolic and clinical features...

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Bibliographic Details
Main Authors: Yangyang Fang, Shunjie Pei, Kaizhao Huang, Feng Xu, Guangxin Xiang, Linhua Lan, Xiaoqun Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
single-cell transcriptome
pancreatic ductal adenocarcinoma
malignant
tumor metabolic
glycolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.798165/full

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